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Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.
Bezzina CR, Barc J, Mizusawa Y, Remme CA, Gourraud JB, Simonet F, Verkerk AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt A, Antzelevitch C, Bartkowiak S, Borggrefe M, Schimpf R, Schulze-Bahr E, Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Olesen MS, Kääb S, Beckmann BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri O, Torchio M, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, Bézieau S, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum P, Portero V, Violleau J, Gessler M, Tan HL, Roden DM, Christoffels VM, Le Marec H, Wilde AA, Probst V, Schott JJ, Dina C, Redon R. Bezzina CR, et al. Among authors: boukens bj. Nat Genet. 2013 Sep;45(9):1044-9. doi: 10.1038/ng.2712. Epub 2013 Jul 21. Nat Genet. 2013. PMID: 23872634 Free PMC article.
Atrial Fibrillation: Biophysics, Molecular Mechanisms, and Novel Therapies.
Glukhov AV, Rosenshtraukh LV, Bhargava A, Miragoli M, Boukens BJ. Glukhov AV, et al. Among authors: boukens bj. Biomed Res Int. 2015;2015:780671. doi: 10.1155/2015/780671. Epub 2015 Jul 9. Biomed Res Int. 2015. PMID: 26240827 Free PMC article. No abstract available.
Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel.
Veldkamp MW, Geuzebroek GSC, Baartscheer A, Verkerk AO, Schumacher CA, Suarez GG, Berger WR, Casini S, van Amersfoorth SCM, Scholman KT, Driessen AHG, Belterman CNW, van Ginneken ACG, de Groot JR, de Bakker JMT, Remme CA, Boukens BJ, Coronel R. Veldkamp MW, et al. Among authors: boukens bj. Nat Commun. 2018 Oct 19;9(1):4357. doi: 10.1038/s41467-018-06530-5. Nat Commun. 2018. PMID: 30341287 Free PMC article.
T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system.
Mohan RA, Bosada FM, van Weerd JH, van Duijvenboden K, Wang J, Mommersteeg MTM, Hooijkaas IB, Wakker V, de Gier-de Vries C, Coronel R, Boink GJJ, Bakkers J, Barnett P, Boukens BJ, Christoffels VM. Mohan RA, et al. Among authors: boukens bj. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18617-18626. doi: 10.1073/pnas.1919379117. Epub 2020 Jul 16. Proc Natl Acad Sci U S A. 2020. PMID: 32675240 Free PMC article.
86 results