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Page 1
Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy.
Binet F, Cagnone G, Crespo-Garcia S, Hata M, Neault M, Dejda A, Wilson AM, Buscarlet M, Mawambo GT, Howard JP, Diaz-Marin R, Parinot C, Guber V, Pilon F, Juneau R, Laflamme R, Sawchyn C, Boulay K, Leclerc S, Abu-Thuraia A, Côté JF, Andelfinger G, Rezende FA, Sennlaub F, Joyal JS, Mallette FA, Sapieha P. Binet F, et al. Among authors: boulay k. Science. 2020 Aug 21;369(6506):eaay5356. doi: 10.1126/science.aay5356. Science. 2020. PMID: 32820093
O-GlcNAcylation of FOXK1 orchestrates the E2F pathway and promotes oncogenesis.
Masclef L, Ahmed O, Iannantuono N, Gagnon J, Gushul-Leclaire M, Boulay K, Estavoyer B, Echbicheb M, Poy M, Boubacar KA, Boubekeur A, Menggad S, Schcolnik-Cabrera A, Balsalobre A, Bonneil E, Thibault P, Hulea L, Tanaka Y, Antoine-Mallette F, Drouin J, Affar EB. Masclef L, et al. Among authors: boulay k. bioRxiv [Preprint]. 2024 Mar 1:2024.03.01.582838. doi: 10.1101/2024.03.01.582838. bioRxiv. 2024. Update in: Nat Commun. 2025 Jul 1;16(1):5959. doi: 10.1038/s41467-025-61022-7. PMID: 38463952 Free PMC article. Updated. Preprint.
mTOR as a central regulator of lifespan and aging.
Papadopoli D, Boulay K, Kazak L, Pollak M, Mallette FA, Topisirovic I, Hulea L. Papadopoli D, et al. Among authors: boulay k. F1000Res. 2019 Jul 2;8:F1000 Faculty Rev-998. doi: 10.12688/f1000research.17196.1. eCollection 2019. F1000Res. 2019. PMID: 31316753 Free PMC article. Review.
Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis.
Uriarte M, Sen Nkwe N, Tremblay R, Ahmed O, Messmer C, Mashtalir N, Barbour H, Masclef L, Voide M, Viallard C, Daou S, Abdelhadi D, Ronato D, Paydar M, Darracq A, Boulay K, Desjardins-Lecavalier N, Sapieha P, Masson JY, Sergeev M, Kwok BH, Hulea L, Mallette FA, Milot E, Larrivée B, Wurtele H, Affar EB. Uriarte M, et al. Among authors: boulay k. Nat Commun. 2021 Nov 30;12(1):6984. doi: 10.1038/s41467-021-27306-4. Nat Commun. 2021. PMID: 34848715 Free PMC article.
An inventory of crosstalk between ubiquitination and other post-translational modifications in orchestrating cellular processes.
Barbour H, Nkwe NS, Estavoyer B, Messmer C, Gushul-Leclaire M, Villot R, Uriarte M, Boulay K, Hlayhel S, Farhat B, Milot E, Mallette FA, Daou S, Affar EB. Barbour H, et al. Among authors: boulay k. iScience. 2023 Feb 26;26(5):106276. doi: 10.1016/j.isci.2023.106276. eCollection 2023 May 19. iScience. 2023. PMID: 37168555 Free PMC article. Review.
CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax.
Neault M, Lebert-Ghali CÉ, Fournier M, Capdevielle C, Garfinkle EAR, Obermayer A, Cotton A, Boulay K, Sawchyn C, St-Amand S, Nguyen KH, Assaf B, Mercier FE, Delisle JS, Drobetsky EA, Hulea L, Shaw TI, Zuber J, Gruber TA, Melichar HJ, Mallette FA. Neault M, et al. Among authors: boulay k. Cell Rep. 2023 Sep 26;42(9):113084. doi: 10.1016/j.celrep.2023.113084. Epub 2023 Sep 15. Cell Rep. 2023. PMID: 37716355 Free article.
R-2-hydroxyglutarate-mediated inhibition of KDM4A compromises telomere integrity.
Couteau F, Gagné LM, Boulay K, Rousseau P, Carbonneau M, McQuaid M, Sharma J, Sawchyn C, Fernandez E, Glatz D, Rizk R, Lalonde ME, Mehrjoo Y, Chu TW, Moquin-Beaudry G, Beauséjour C, Sergeev M, Costantino S, Avizonis D, Topisirovic I, Jabado N, Wurtele H, Autexier C, Mallette FA. Couteau F, et al. Among authors: boulay k. Nucleic Acids Res. 2025 Jun 6;53(11):gkaf512. doi: 10.1093/nar/gkaf512. Nucleic Acids Res. 2025. PMID: 40498073 Free PMC article.
O-GlcNAcylation of FOXK1 co-opts BAP1 to orchestrate the E2F pathway and promotes oncogenesis.
Ahmed O, Masclef L, Iannantuono N, Gagnon J, Gushul-Leclaire M, Boulay K, Estavoyer B, Echbicheb M, Ali Boubacar K, Poy M, Boubekeur A, Menggad S, Schcolnik-Cabrera A, Balsalobre A, Bonneil E, Thibault P, Hulea L, Mallette FA, Drouin J, Tanaka Y, Affar EB. Ahmed O, et al. Among authors: boulay k. Nat Commun. 2025 Jul 1;16(1):5959. doi: 10.1038/s41467-025-61022-7. Nat Commun. 2025. PMID: 40593803 Free PMC article.
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