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The immunological and genetic basis of inflammatory bowel disease.
Bouma G, Strober W. Bouma G, et al. Nat Rev Immunol. 2003 Jul;3(7):521-33. doi: 10.1038/nri1132. Nat Rev Immunol. 2003. PMID: 12876555 Review.
Cutting edge: a variant of the IL-23R gene associated with inflammatory bowel disease induces loss of microRNA regulation and enhanced protein production.
Zwiers A, Kraal L, van de Pouw Kraan TC, Wurdinger T, Bouma G, Kraal G. Zwiers A, et al. Among authors: bouma g. J Immunol. 2012 Feb 15;188(4):1573-7. doi: 10.4049/jimmunol.1101494. Epub 2012 Jan 18. J Immunol. 2012. PMID: 22262659
Recent advances in the etiology and treatment of inflammatory bowel disease.
Zwiers A, Bouma G. Zwiers A, et al. Among authors: bouma g. Expert Rev Clin Immunol. 2006 Mar;2(2):245-56. doi: 10.1586/1744666X.2.2.245. Expert Rev Clin Immunol. 2006. PMID: 20477075
Secretion of tumour necrosis factor alpha and lymphotoxin alpha in relation to polymorphisms in the TNF genes and HLA-DR alleles. Relevance for inflammatory bowel disease.
Bouma G, Crusius JB, Oudkerk Pool M, Kolkman JJ, von Blomberg BM, Kostense PJ, Giphart MJ, Schreuder GM, Meuwissen SG, Peña AS. Bouma G, et al. Scand J Immunol. 1996 Apr;43(4):456-63. doi: 10.1046/j.1365-3083.1996.d01-65.x. Scand J Immunol. 1996. PMID: 8668926
Distribution of four polymorphisms in the tumour necrosis factor (TNF) genes in patients with inflammatory bowel disease (IBD).
Bouma G, Xia B, Crusius JB, Bioque G, Koutroubakis I, Von Blomberg BM, Meuwissen SG, Peña AS. Bouma G, et al. Clin Exp Immunol. 1996 Mar;103(3):391-6. doi: 10.1111/j.1365-2249.1996.tb08292.x. Clin Exp Immunol. 1996. PMID: 8608636 Free PMC article.
Allelic polymorphism in IL-1 beta and IL-1 receptor antagonist (IL-1Ra) genes in inflammatory bowel disease.
Bioque G, Crusius JB, Koutroubakis I, Bouma G, Kostense PJ, Meuwissen SG, Peña AS. Bioque G, et al. Among authors: bouma g. Clin Exp Immunol. 1995 Nov;102(2):379-83. doi: 10.1111/j.1365-2249.1995.tb03793.x. Clin Exp Immunol. 1995. PMID: 7586694 Free PMC article.
[Immunology in medical practice. XXVI. Immunogenetics of chronic inflammatory bowel diseases].
Bouma G, Peña AS. Bouma G, et al. Ned Tijdschr Geneeskd. 1999 Nov 27;143(48):2414-20. Ned Tijdschr Geneeskd. 1999. PMID: 10608975 Review. Dutch.
Experimental murine colitis is regulated by two genetic loci, including one on chromosome 11 that regulates IL-12 responses.
Bouma G, Kaushiva A, Strober W. Bouma G, et al. Gastroenterology. 2002 Aug;123(2):554-65. doi: 10.1053/gast.2002.34752. Gastroenterology. 2002. PMID: 12145808
A TaqI polymorphism in the 3'UTR of the IL-12 p40 gene correlates with increased IL-12 secretion.
Seegers D, Zwiers A, Strober W, Peña AS, Bouma G. Seegers D, et al. Among authors: bouma g. Genes Immun. 2002 Nov;3(7):419-23. doi: 10.1038/sj.gene.6363919. Genes Immun. 2002. PMID: 12424624
Cohort profile: design and first results of the Dutch IBD Biobank: a prospective, nationwide biobank of patients with inflammatory bowel disease.
Spekhorst LM, Imhann F, Festen EAM, van Bodegraven AA, de Boer NKH, Bouma G, Fidder HH, d'Haens G, Hoentjen F, Hommes DW, de Jong DJ, Löwenberg M, Maljaars PWJ, van der Meulen-de Jong AE, Oldenburg B, Pierik MJ, Ponsioen CY, Stokkers PC, Verspaget HW, Visschedijk MC, van der Woude CJ, Dijkstra G, Weersma RK; Parelsnoer Institute (PSI) and the Dutch Initiative on Crohn and Colitis (ICC). Spekhorst LM, et al. Among authors: bouma g. BMJ Open. 2017 Nov 8;7(11):e016695. doi: 10.1136/bmjopen-2017-016695. BMJ Open. 2017. PMID: 29122790 Free PMC article.
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