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Sox9/Sox6 and Sp1 are involved in the insulin-like growth factor-I-mediated upregulation of human type II collagen gene expression in articular chondrocytes.
Renard E, Porée B, Chadjichristos C, Kypriotou M, Maneix L, Bigot N, Legendre F, Ollitrault D, De Crombrugghe B, Malléin-Gérin F, Moslemi S, Demoor M, Boumediene K, Galéra P. Renard E, et al. Among authors: boumediene k. J Mol Med (Berl). 2012 Jun;90(6):649-66. doi: 10.1007/s00109-011-0842-3. Epub 2012 Jan 4. J Mol Med (Berl). 2012. PMID: 22215151
17Beta-oestradiol up-regulates the expression of a functional UDP-glucose dehydrogenase in articular chondrocytes: comparison with effects of cytokines and growth factors.
Maneix L, Beauchef G, Servent A, Wegrowski Y, Maquart FX, Boujrad N, Flouriot G, Pujol JP, Boumediene K, Galéra P, Moslemi S. Maneix L, et al. Among authors: boumediene k. Rheumatology (Oxford). 2008 Mar;47(3):281-8. doi: 10.1093/rheumatology/kem323. Epub 2008 Jan 31. Rheumatology (Oxford). 2008. PMID: 18238796
The p65 subunit of NF-κB inhibits COL1A1 gene transcription in human dermal and scleroderma fibroblasts through its recruitment on promoter by protein interaction with transcriptional activators (c-Krox, Sp1, and Sp3).
Beauchef G, Bigot N, Kypriotou M, Renard E, Porée B, Widom R, Dompmartin-Blanchere A, Oddos T, Maquart FX, Demoor M, Boumediene K, Galera P. Beauchef G, et al. Among authors: boumediene k. J Biol Chem. 2012 Jan 27;287(5):3462-78. doi: 10.1074/jbc.M111.286443. Epub 2011 Dec 2. J Biol Chem. 2012. PMID: 22139845 Free PMC article.
Interleukin-6 (IL-6) and/or soluble IL-6 receptor down-regulation of human type II collagen gene expression in articular chondrocytes requires a decrease of Sp1.Sp3 ratio and of the binding activity of both factors to the COL2A1 promoter.
Porée B, Kypriotou M, Chadjichristos C, Beauchef G, Renard E, Legendre F, Melin M, Gueret S, Hartmann DJ, Malléin-Gerin F, Pujol JP, Boumediene K, Galéra P. Porée B, et al. Among authors: boumediene k. J Biol Chem. 2008 Feb 22;283(8):4850-65. doi: 10.1074/jbc.M706387200. Epub 2007 Dec 7. J Biol Chem. 2008. PMID: 18065760 Free article.
Hypoxia-inducible factor 1alpha inhibits the fibroblast-like markers type I and type III collagen during hypoxia-induced chondrocyte redifferentiation: hypoxia not only induces type II collagen and aggrecan, but it also inhibits type I and type III collagen in the hypoxia-inducible factor 1alpha-dependent redifferentiation of chondrocytes.
Duval E, Leclercq S, Elissalde JM, Demoor M, Galéra P, Boumédiene K. Duval E, et al. Among authors: boumediene k. Arthritis Rheum. 2009 Oct;60(10):3038-48. doi: 10.1002/art.24851. Arthritis Rheum. 2009. PMID: 19790048 Free article.
Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta.
Baugé C, Cauvard O, Leclercq S, Galéra P, Boumédiene K. Baugé C, et al. Among authors: boumediene k. Arthritis Res Ther. 2011 Feb 15;13(1):R23. doi: 10.1186/ar3247. Arthritis Res Ther. 2011. PMID: 21324108 Free PMC article.
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