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Potential mechanisms of interleukin-1 involvement in cerebral ischaemia.
Touzani O, Boutin H, Chuquet J, Rothwell N. Touzani O, et al. Among authors: boutin h. J Neuroimmunol. 1999 Dec;100(1-2):203-15. doi: 10.1016/s0165-5728(99)00202-7. J Neuroimmunol. 1999. PMID: 10695731 Review.
Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia.
Pradillo JM, Murray KN, Coutts GA, Moraga A, Oroz-Gonjar F, Boutin H, Moro MA, Lizasoain I, Rothwell NJ, Allan SM. Pradillo JM, et al. Among authors: boutin h. Brain Behav Immun. 2017 Mar;61:117-126. doi: 10.1016/j.bbi.2016.11.013. Epub 2016 Nov 14. Brain Behav Immun. 2017. PMID: 27856349 Free PMC article.
Delayed administration of interleukin-1 receptor antagonist reduces ischemic brain damage and inflammation in comorbid rats.
Pradillo JM, Denes A, Greenhalgh AD, Boutin H, Drake C, McColl BW, Barton E, Proctor SD, Russell JC, Rothwell NJ, Allan SM. Pradillo JM, et al. Among authors: boutin h. J Cereb Blood Flow Metab. 2012 Sep;32(9):1810-9. doi: 10.1038/jcbfm.2012.101. Epub 2012 Jul 11. J Cereb Blood Flow Metab. 2012. PMID: 22781338 Free PMC article.
Long-term alterations in mu, delta and kappa opioidergic receptors following middle cerebral artery occlusion in mice.
Boutin H, Catherine A, Mackenzie ET, Jauzac P, Dauphin F. Boutin H, et al. Acta Neuropathol. 2007 Nov;114(5):491-500. doi: 10.1007/s00401-007-0269-7. Epub 2007 Aug 4. Acta Neuropathol. 2007. PMID: 17676326
The expanding interleukin-1 family and its receptors: do alternative IL-1 receptor/signaling pathways exist in the brain?
Boutin H, Kimber I, Rothwell NJ, Pinteaux E. Boutin H, et al. Mol Neurobiol. 2003 Jun;27(3):239-48. doi: 10.1385/MN:27:3:239. Mol Neurobiol. 2003. PMID: 12845150 Review.
[18F]DPA-714: direct comparison with [11C]PK11195 in a model of cerebral ischemia in rats.
Boutin H, Prenant C, Maroy R, Galea J, Greenhalgh AD, Smigova A, Cawthorne C, Julyan P, Wilkinson SM, Banister SD, Brown G, Herholz K, Kassiou M, Rothwell NJ. Boutin H, et al. PLoS One. 2013;8(2):e56441. doi: 10.1371/journal.pone.0056441. Epub 2013 Feb 13. PLoS One. 2013. PMID: 23418569 Free PMC article.
To solve this issue of inter-individual variability, we performed a direct comparison of [(11)C]PK11195 and [(18)F]DPA-714 by scanning the same animals sequentially with both tracers within 24 h. ...
To solve this issue of inter-individual variability, we performed a direct comparison of [(11)C]PK11195 and [(18)F]DPA-714 by scanning the s …
Assessing the contribution of inflammation in models of Alzheimer's disease.
Johnston H, Boutin H, Allan SM. Johnston H, et al. Among authors: boutin h. Biochem Soc Trans. 2011 Aug;39(4):886-90. doi: 10.1042/BST0390886. Biochem Soc Trans. 2011. PMID: 21787318 Review.
Brain inflammation is induced by co-morbidities and risk factors for stroke.
Drake C, Boutin H, Jones MS, Denes A, McColl BW, Selvarajah JR, Hulme S, Georgiou RF, Hinz R, Gerhard A, Vail A, Prenant C, Julyan P, Maroy R, Brown G, Smigova A, Herholz K, Kassiou M, Crossman D, Francis S, Proctor SD, Russell JC, Hopkins SJ, Tyrrell PJ, Rothwell NJ, Allan SM. Drake C, et al. Among authors: boutin h. Brain Behav Immun. 2011 Aug;25(6):1113-22. doi: 10.1016/j.bbi.2011.02.008. Epub 2011 Feb 26. Brain Behav Immun. 2011. PMID: 21356305 Free PMC article.
Neuroprotective actions of endogenous interleukin-1 receptor antagonist (IL-1ra) are mediated by glia.
Pinteaux E, Rothwell NJ, Boutin H. Pinteaux E, et al. Among authors: boutin h. Glia. 2006 Apr 1;53(5):551-6. doi: 10.1002/glia.20308. Glia. 2006. PMID: 16374779
Interleukin-1 influences ischemic brain damage in the mouse independently of the interleukin-1 type I receptor.
Touzani O, Boutin H, LeFeuvre R, Parker L, Miller A, Luheshi G, Rothwell N. Touzani O, et al. Among authors: boutin h. J Neurosci. 2002 Jan 1;22(1):38-43. doi: 10.1523/JNEUROSCI.22-01-00038.2002. J Neurosci. 2002. PMID: 11756486 Free PMC article.
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