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Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase.
Hernández-Muñoz I, Lund AH, van der Stoop P, Boutsma E, Muijrers I, Verhoeven E, Nusinow DA, Panning B, Marahrens Y, van Lohuizen M. Hernández-Muñoz I, et al. Among authors: boutsma e. Proc Natl Acad Sci U S A. 2005 May 24;102(21):7635-40. doi: 10.1073/pnas.0408918102. Epub 2005 May 16. Proc Natl Acad Sci U S A. 2005. PMID: 15897469 Free PMC article.
Emerging roles of Polycomb silencing in X-inactivation and stem cell maintenance.
Muyrers-Chen I, Hernández-Muñoz I, Lund AH, Valk-Lingbeek ME, van der Stoop P, Boutsma E, Tolhuis B, Bruggeman SW, Taghavi P, Verhoeven E, Hulsman D, Noback S, Tanger E, Theunissen H, van Lohuizen M. Muyrers-Chen I, et al. Among authors: boutsma e. Cold Spring Harb Symp Quant Biol. 2004;69:319-26. doi: 10.1101/sqb.2004.69.319. Cold Spring Harb Symp Quant Biol. 2004. PMID: 16117664 Review. No abstract available.