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Regulation of the activity of Sp1-related transcription factors.
Bouwman P, Philipsen S. Bouwman P, et al. Mol Cell Endocrinol. 2002 Sep 30;195(1-2):27-38. doi: 10.1016/s0303-7207(02)00221-6. Mol Cell Endocrinol. 2002. PMID: 12354670 Review.
Defective paracrine signalling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia.
Carvalho RL, Jonker L, Goumans MJ, Larsson J, Bouwman P, Karlsson S, Dijke PT, Arthur HM, Mummery CL. Carvalho RL, et al. Among authors: bouwman p. Development. 2004 Dec;131(24):6237-47. doi: 10.1242/dev.01529. Epub 2004 Nov 17. Development. 2004. PMID: 15548578
Impaired hematopoiesis in mice lacking the transcription factor Sp3.
Van Loo PF, Bouwman P, Ling KW, Middendorp S, Suske G, Grosveld F, Dzierzak E, Philipsen S, Hendriks RW. Van Loo PF, et al. Among authors: bouwman p. Blood. 2003 Aug 1;102(3):858-66. doi: 10.1182/blood-2002-06-1848. Epub 2003 Apr 3. Blood. 2003. PMID: 12676787
Transcription factor Sp3 is essential for post-natal survival and late tooth development.
Bouwman P, Göllner H, Elsässer HP, Eckhoff G, Karis A, Grosveld F, Philipsen S, Suske G. Bouwman P, et al. EMBO J. 2000 Feb 15;19(4):655-61. doi: 10.1093/emboj/19.4.655. EMBO J. 2000. PMID: 10675334 Free PMC article.
Complex phenotype of mice homozygous for a null mutation in the Sp4 transcription factor gene.
Göllner H, Bouwman P, Mangold M, Karis A, Braun H, Rohner I, Del Rey A, Besedovsky HO, Meinhardt A, van den Broek M, Cutforth T, Grosveld F, Philipsen S, Suske G. Göllner H, et al. Among authors: bouwman p. Genes Cells. 2001 Aug;6(8):689-97. doi: 10.1046/j.1365-2443.2001.00455.x. Genes Cells. 2001. PMID: 11532028
Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development.
van Meeteren LA, Ruurs P, Stortelers C, Bouwman P, van Rooijen MA, Pradère JP, Pettit TR, Wakelam MJ, Saulnier-Blache JS, Mummery CL, Moolenaar WH, Jonkers J. van Meeteren LA, et al. Among authors: bouwman p. Mol Cell Biol. 2006 Jul;26(13):5015-22. doi: 10.1128/MCB.02419-05. Mol Cell Biol. 2006. PMID: 16782887 Free PMC article.
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.
Bouwman P, Aly A, Escandell JM, Pieterse M, Bartkova J, van der Gulden H, Hiddingh S, Thanasoula M, Kulkarni A, Yang Q, Haffty BG, Tommiska J, Blomqvist C, Drapkin R, Adams DJ, Nevanlinna H, Bartek J, Tarsounas M, Ganesan S, Jonkers J. Bouwman P, et al. Nat Struct Mol Biol. 2010 Jun;17(6):688-95. doi: 10.1038/nsmb.1831. Epub 2010 May 9. Nat Struct Mol Biol. 2010. PMID: 20453858 Free PMC article.
Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression.
Bouwman P, Drost R, Klijn C, Pieterse M, van der Gulden H, Song JY, Szuhai K, Jonkers J. Bouwman P, et al. J Pathol. 2011 May;224(1):10-21. doi: 10.1002/path.2861. Epub 2011 Mar 14. J Pathol. 2011. PMID: 21404276
BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.
Drost R, Bouwman P, Rottenberg S, Boon U, Schut E, Klarenbeek S, Klijn C, van der Heijden I, van der Gulden H, Wientjens E, Pieterse M, Catteau A, Green P, Solomon E, Morris JR, Jonkers J. Drost R, et al. Among authors: bouwman p. Cancer Cell. 2011 Dec 13;20(6):797-809. doi: 10.1016/j.ccr.2011.11.014. Cancer Cell. 2011. PMID: 22172724
Suppression of BRCA1 sensitizes cells to proteasome inhibitors.
Gu Y, Bouwman P, Greco D, Saarela J, Yadav B, Jonkers J, Kuznetsov SG. Gu Y, et al. Among authors: bouwman p. Cell Death Dis. 2014 Dec 18;5(12):e1580. doi: 10.1038/cddis.2014.537. Cell Death Dis. 2014. PMID: 25522274 Free PMC article.
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