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39 results
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Brain drains: new insights into brain clearance pathways from lymphatic biology.
Bower NI, Hogan BM. Bower NI, et al. J Mol Med (Berl). 2018 May;96(5):383-390. doi: 10.1007/s00109-018-1634-9. Epub 2018 Apr 2. J Mol Med (Berl). 2018. PMID: 29610928 Review.
Mural lymphatic endothelial cells regulate meningeal angiogenesis in the zebrafish.
Bower NI, Koltowska K, Pichol-Thievend C, Virshup I, Paterson S, Lagendijk AK, Wang W, Lindsey BW, Bent SJ, Baek S, Rondon-Galeano M, Hurley DG, Mochizuki N, Simons C, Francois M, Wells CA, Kaslin J, Hogan BM. Bower NI, et al. Nat Neurosci. 2017 Jun;20(6):774-783. doi: 10.1038/nn.4558. Epub 2017 May 1. Nat Neurosci. 2017. PMID: 28459441
Vegfa signaling promotes zebrafish intestinal vasculature development through endothelial cell migration from the posterior cardinal vein.
Koenig AL, Baltrunaite K, Bower NI, Rossi A, Stainier DY, Hogan BM, Sumanas S. Koenig AL, et al. Among authors: bower ni. Dev Biol. 2016 Mar 1;411(1):115-27. doi: 10.1016/j.ydbio.2016.01.002. Epub 2016 Jan 6. Dev Biol. 2016. PMID: 26769101 Free PMC article.
mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish.
Koltowska K, Paterson S, Bower NI, Baillie GJ, Lagendijk AK, Astin JW, Chen H, Francois M, Crosier PS, Taft RJ, Simons C, Smith KA, Hogan BM. Koltowska K, et al. Among authors: bower ni. Genes Dev. 2015 Aug 1;29(15):1618-30. doi: 10.1101/gad.263210.115. Genes Dev. 2015. PMID: 26253536 Free PMC article.
Pkd1 regulates lymphatic vascular morphogenesis during development.
Coxam B, Sabine A, Bower NI, Smith KA, Pichol-Thievend C, Skoczylas R, Astin JW, Frampton E, Jaquet M, Crosier PS, Parton RG, Harvey NL, Petrova TV, Schulte-Merker S, Francois M, Hogan BM. Coxam B, et al. Among authors: bower ni. Cell Rep. 2014 May 8;7(3):623-33. doi: 10.1016/j.celrep.2014.03.063. Epub 2014 Apr 24. Cell Rep. 2014. PMID: 24767999 Free PMC article.
Arap3 is dysregulated in a mouse model of hypotrichosis-lymphedema-telangiectasia and regulates lymphatic vascular development.
Kartopawiro J, Bower NI, Karnezis T, Kazenwadel J, Betterman KL, Lesieur E, Koltowska K, Astin J, Crosier P, Vermeren S, Achen MG, Stacker SA, Smith KA, Harvey NL, Fran├žois M, Hogan BM. Kartopawiro J, et al. Among authors: bower ni. Hum Mol Genet. 2014 Mar 1;23(5):1286-97. doi: 10.1093/hmg/ddt518. Epub 2013 Oct 24. Hum Mol Genet. 2014. PMID: 24163130
The Alternative Splicing Regulator Nova2 Constrains Vascular Erk Signaling to Limit Specification of the Lymphatic Lineage.
Baek S, Oh TG, Secker G, Sutton DL, Okuda KS, Paterson S, Bower NI, Toubia J, Koltowska K, Capon SJ, Baillie GJ, Simons C, Muscat GEO, Lagendijk AK, Smith KA, Harvey NL, Hogan BM. Baek S, et al. Among authors: bower ni. Dev Cell. 2019 Apr 22;49(2):279-292.e5. doi: 10.1016/j.devcel.2019.03.017. Dev Cell. 2019. PMID: 31014480 Free article.
Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling.
Williams SP, Odell AF, Karnezis T, Farnsworth RH, Gould CM, Li J, Paquet-Fifield S, Harris NC, Walter A, Gregory JL, Lamont SF, Liu R, Takano EA, Nowell CJ, Bower NI, Resnick D, Smyth GK, Coultas L, Hogan BM, Fox SB, Mueller SN, Simpson KJ, Achen MG, Stacker SA. Williams SP, et al. Among authors: bower ni. Sci Signal. 2017 Oct 3;10(499):eaal2987. doi: 10.1126/scisignal.aal2987. Sci Signal. 2017. PMID: 28974649
Vegfd modulates both angiogenesis and lymphangiogenesis during zebrafish embryonic development.
Bower NI, Vogrin AJ, Le Guen L, Chen H, Stacker SA, Achen MG, Hogan BM. Bower NI, et al. Development. 2017 Feb 1;144(3):507-518. doi: 10.1242/dev.146969. Epub 2017 Jan 13. Development. 2017. PMID: 28087639
Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis.
Le Guen L, Karpanen T, Schulte D, Harris NC, Koltowska K, Roukens G, Bower NI, van Impel A, Stacker SA, Achen MG, Schulte-Merker S, Hogan BM. Le Guen L, et al. Among authors: bower ni. Development. 2014 Mar;141(6):1239-49. doi: 10.1242/dev.100495. Epub 2014 Feb 12. Development. 2014. PMID: 24523457
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