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Inhibition of Siah ubiquitin ligase function.
Möller A, House CM, Wong CS, Scanlon DB, Liu MC, Ronai Z, Bowtell DD. Möller A, et al. Among authors: bowtell dd. Oncogene. 2009 Jan 15;28(2):289-96. doi: 10.1038/onc.2008.382. Epub 2008 Oct 13. Oncogene. 2009. PMID: 18850011 Free PMC article.
Generation and analysis of Siah2 mutant mice.
Frew IJ, Hammond VE, Dickins RA, Quinn JM, Walkley CR, Sims NA, Schnall R, Della NG, Holloway AJ, Digby MR, Janes PW, Tarlinton DM, Purton LE, Gillespie MT, Bowtell DD. Frew IJ, et al. Among authors: bowtell dd. Mol Cell Biol. 2003 Dec;23(24):9150-61. doi: 10.1128/MCB.23.24.9150-9161.2003. Mol Cell Biol. 2003. PMID: 14645526 Free PMC article.
A binding motif for Siah ubiquitin ligase.
House CM, Frew IJ, Huang HL, Wiche G, Traficante N, Nice E, Catimel B, Bowtell DD. House CM, et al. Among authors: bowtell dd. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3101-6. doi: 10.1073/pnas.0534783100. Epub 2003 Mar 7. Proc Natl Acad Sci U S A. 2003. PMID: 12626763 Free PMC article.
Elucidation of the substrate binding site of Siah ubiquitin ligase.
House CM, Hancock NC, Möller A, Cromer BA, Fedorov V, Bowtell DD, Parker MW, Polekhina G. House CM, et al. Among authors: bowtell dd. Structure. 2006 Apr;14(4):695-701. doi: 10.1016/j.str.2005.12.013. Structure. 2006. PMID: 16615911
Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.
Anglesio MS, Arnold JM, George J, Tinker AV, Tothill R, Waddell N, Simms L, Locandro B, Fereday S, Traficante N, Russell P, Sharma R, Birrer MJ; AOCS Study Group, deFazio A, Chenevix-Trench G, Bowtell DD. Anglesio MS, et al. Among authors: bowtell dd. Mol Cancer Res. 2008 Nov;6(11):1678-90. doi: 10.1158/1541-7786.MCR-08-0193. Mol Cancer Res. 2008. PMID: 19010816 Free PMC article.
Osteopenia in Siah1a mutant mice.
Frew IJ, Sims NA, Quinn JM, Walkley CR, Purton LE, Bowtell DD, Gillespie MT. Frew IJ, et al. Among authors: bowtell dd. J Biol Chem. 2004 Jul 9;279(28):29583-8. doi: 10.1074/jbc.M312755200. Epub 2004 May 3. J Biol Chem. 2004. PMID: 15123657
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