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The role of genetic variants in CYP2C8, LPIN1, PPARGC1A and PPARγ on the trough steady-state plasma concentrations of rosiglitazone and on glycosylated haemoglobin A1c in type 2 diabetes.
Stage TB, Christensen MM, Feddersen S, Beck-Nielsen H, Brøsen K. Stage TB, et al. Among authors: brosen k. Pharmacogenet Genomics. 2013 Apr;23(4):219-27. doi: 10.1097/FPC.0b013e32835f91fc. Pharmacogenet Genomics. 2013. PMID: 23426382
The selective serotonin reuptake inhibitor citalopram relieves the symptoms of diabetic neuropathy.
Sindrup SH, Bjerre U, Dejgaard A, Brøsen K, Aaes-Jørgensen T, Gram LF. Sindrup SH, et al. Among authors: brosen k. Clin Pharmacol Ther. 1992 Nov;52(5):547-52. doi: 10.1038/clpt.1992.183. Clin Pharmacol Ther. 1992. PMID: 1424428 Clinical Trial.
Lack of effect of mianserin on the symptoms of diabetic neuropathy.
Sindrup SH, Tuxen C, Gram LF, Grodum E, Skjold T, Brøsen K, Beck-Nielsen H. Sindrup SH, et al. Among authors: brosen k. Eur J Clin Pharmacol. 1992;43(3):251-5. doi: 10.1007/BF02333018. Eur J Clin Pharmacol. 1992. PMID: 1425887 Clinical Trial.
Steady-state plasma levels of clomipramine and its metabolites: impact of the sparteine/debrisoquine oxidation polymorphism. Danish University Antidepressant Group.
Nielsen KK, Brøsen K, Gram LF. Nielsen KK, et al. Among authors: brosen k. Eur J Clin Pharmacol. 1992;43(4):405-11. doi: 10.1007/BF02220617. Eur J Clin Pharmacol. 1992. PMID: 1451721 Clinical Trial.
Pharmacogenetics in psychopharmacology: basic principles and clinical implications.
Gram LF, Brøsen K, Sindrup S, Skjelbo E, Nielsen KK. Gram LF, et al. Among authors: brosen k. Clin Neuropharmacol. 1992;15 Suppl 1 Pt A:76A-77A. Clin Neuropharmacol. 1992. PMID: 1499003 No abstract available.
The relationship between paroxetine and the sparteine oxidation polymorphism.
Sindrup SH, Brøsen K, Gram LF, Hallas J, Skjelbo E, Allen A, Allen GD, Cooper SM, Mellows G, Tasker TC, et al. Sindrup SH, et al. Among authors: brosen k. Clin Pharmacol Ther. 1992 Mar;51(3):278-87. doi: 10.1038/clpt.1992.23. Clin Pharmacol Ther. 1992. PMID: 1531950
Pharmacokinetics of the selective serotonin reuptake inhibitor paroxetine: nonlinearity and relation to the sparteine oxidation polymorphism.
Sindrup SH, Brøsen K, Gram LF. Sindrup SH, et al. Among authors: brosen k. Clin Pharmacol Ther. 1992 Mar;51(3):288-95. doi: 10.1038/clpt.1992.24. Clin Pharmacol Ther. 1992. PMID: 1531951
Clomipramine vs desipramine vs placebo in the treatment of diabetic neuropathy symptoms. A double-blind cross-over study.
Sindrup SH, Gram LF, Skjold T, Grodum E, Brøsen K, Beck-Nielsen H. Sindrup SH, et al. Among authors: brosen k. Br J Clin Pharmacol. 1990 Nov;30(5):683-91. doi: 10.1111/j.1365-2125.1990.tb03836.x. Br J Clin Pharmacol. 1990. PMID: 2271367 Free PMC article. Clinical Trial.
Nonlinear kinetics of imipramine in low and medium plasma level ranges.
Sindrup SH, Brøsen K, Gram LF. Sindrup SH, et al. Among authors: brosen k. Ther Drug Monit. 1990 Sep;12(5):445-9. doi: 10.1097/00007691-199009000-00007. Ther Drug Monit. 1990. PMID: 2293406
Steady-state plasma levels of E- and Z-10-OH-nortriptyline in nortriptyline-treated patients: significance of concurrent medication and the sparteine oxidation phenotype.
Gram LF, Brøsen K, Kragh-Sørensen P, Christensen P. Gram LF, et al. Among authors: brosen k. Ther Drug Monit. 1989 Sep;11(5):508-14. doi: 10.1097/00007691-198909000-00003. Ther Drug Monit. 1989. PMID: 2815225
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