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The role of insulin receptor signaling in the brain.
Plum L, Schubert M, Brüning JC. Plum L, et al. Among authors: bruning jc. Trends Endocrinol Metab. 2005 Mar;16(2):59-65. doi: 10.1016/j.tem.2005.01.008. Trends Endocrinol Metab. 2005. PMID: 15734146 Review.
Agouti-related peptide-expressing neurons are mandatory for feeding.
Gropp E, Shanabrough M, Borok E, Xu AW, Janoschek R, Buch T, Plum L, Balthasar N, Hampel B, Waisman A, Barsh GS, Horvath TL, Brüning JC. Gropp E, et al. Among authors: bruning jc. Nat Neurosci. 2005 Oct;8(10):1289-91. doi: 10.1038/nn1548. Epub 2005 Sep 11. Nat Neurosci. 2005. PMID: 16158063
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.
Plum L, Ma X, Hampel B, Balthasar N, Coppari R, Münzberg H, Shanabrough M, Burdakov D, Rother E, Janoschek R, Alber J, Belgardt BF, Koch L, Seibler J, Schwenk F, Fekete C, Suzuki A, Mak TW, Krone W, Horvath TL, Ashcroft FM, Brüning JC. Plum L, et al. Among authors: bruning jc. J Clin Invest. 2006 Jul;116(7):1886-901. doi: 10.1172/JCI27123. Epub 2006 Jun 22. J Clin Invest. 2006. PMID: 16794735 Free PMC article.
239 results