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Gastrointestinal stem cells in development and cancer.
Brabletz S, Schmalhofer O, Brabletz T. Brabletz S, et al. Among authors: brabletz t. J Pathol. 2009 Jan;217(2):307-17. doi: 10.1002/path.2475. J Pathol. 2009. PMID: 19031475 Review.
Detection of disseminated tumour cells in mediastinoscopic lymph node biopsies and endobronchial ultrasonography-guided transbronchial needle aspiration in patients with suspected lung cancer.
Dango S, Cucuruz B, Mayer O, Brabletz S, Follo M, Elze M, Sienel W, Brabletz T, Passlick B. Dango S, et al. Among authors: brabletz t, brabletz s. Lung Cancer. 2010 Jun;68(3):383-8. doi: 10.1016/j.lungcan.2009.08.003. Epub 2009 Sep 4. Lung Cancer. 2010. PMID: 19733415 Clinical Trial.
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
Wellner U, Schubert J, Burk UC, Schmalhofer O, Zhu F, Sonntag A, Waldvogel B, Vannier C, Darling D, zur Hausen A, Brunton VG, Morton J, Sansom O, Schüler J, Stemmler MP, Herzberger C, Hopt U, Keck T, Brabletz S, Brabletz T. Wellner U, et al. Among authors: brabletz t, brabletz s. Nat Cell Biol. 2009 Dec;11(12):1487-95. doi: 10.1038/ncb1998. Epub 2009 Nov 22. Nat Cell Biol. 2009. PMID: 19935649
The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells.
Brabletz S, Bajdak K, Meidhof S, Burk U, Niedermann G, Firat E, Wellner U, Dimmler A, Faller G, Schubert J, Brabletz T. Brabletz S, et al. Among authors: brabletz t. EMBO J. 2011 Feb 16;30(4):770-82. doi: 10.1038/emboj.2010.349. Epub 2011 Jan 11. EMBO J. 2011. PMID: 21224848 Free PMC article.
The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance.
Siebzehnrubl FA, Silver DJ, Tugertimur B, Deleyrolle LP, Siebzehnrubl D, Sarkisian MR, Devers KG, Yachnis AT, Kupper MD, Neal D, Nabilsi NH, Kladde MP, Suslov O, Brabletz S, Brabletz T, Reynolds BA, Steindler DA. Siebzehnrubl FA, et al. Among authors: brabletz t, brabletz s. EMBO Mol Med. 2013 Aug;5(8):1196-212. doi: 10.1002/emmm.201302827. Epub 2013 Jul 1. EMBO Mol Med. 2013. PMID: 23818228 Free PMC article.
ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat.
Meidhof S, Brabletz S, Lehmann W, Preca BT, Mock K, Ruh M, Schüler J, Berthold M, Weber A, Burk U, Lübbert M, Puhr M, Culig Z, Wellner U, Keck T, Bronsert P, Küsters S, Hopt UT, Stemmler MP, Brabletz T. Meidhof S, et al. Among authors: brabletz t, brabletz s. EMBO Mol Med. 2015 Jun;7(6):831-47. doi: 10.15252/emmm.201404396. EMBO Mol Med. 2015. PMID: 25872941 Free PMC article.
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