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Cyclophosphamide enhances the antitumor efficacy of adoptively transferred immune cells through the induction of cytokine expression, B-cell and T-cell homeostatic proliferation, and specific tumor infiltration.
Bracci L, Moschella F, Sestili P, La Sorsa V, Valentini M, Canini I, Baccarini S, Maccari S, Ramoni C, Belardelli F, Proietti E. Bracci L, et al. Clin Cancer Res. 2007 Jan 15;13(2 Pt 1):644-53. doi: 10.1158/1078-0432.CCR-06-1209. Clin Cancer Res. 2007. PMID: 17255288
Chemotherapy enhances vaccine-induced antitumor immunity in melanoma patients.
Nisticò P, Capone I, Palermo B, Del Bello D, Ferraresi V, Moschella F, Aricò E, Valentini M, Bracci L, Cognetti F, Ciccarese M, Vercillo G, Roselli M, Fossile E, Tosti ME, Wang E, Marincola F, Imberti L, Catricalà C, Natali PG, Belardelli F, Proietti E. Nisticò P, et al. Among authors: bracci l. Int J Cancer. 2009 Jan 1;124(1):130-9. doi: 10.1002/ijc.23886. Int J Cancer. 2009. PMID: 18839429 Clinical Trial.
Type I IFN regulate DC turnover in vivo.
Mattei F, Bracci L, Tough DF, Belardelli F, Schiavoni G. Mattei F, et al. Among authors: bracci l. Eur J Immunol. 2009 Jul;39(7):1807-18. doi: 10.1002/eji.200939233. Eur J Immunol. 2009. PMID: 19544312
Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis.
Schiavoni G, Sistigu A, Valentini M, Mattei F, Sestili P, Spadaro F, Sanchez M, Lorenzi S, D'Urso MT, Belardelli F, Gabriele L, Proietti E, Bracci L. Schiavoni G, et al. Among authors: bracci l. Cancer Res. 2011 Feb 1;71(3):768-78. doi: 10.1158/0008-5472.CAN-10-2788. Epub 2010 Dec 13. Cancer Res. 2011. PMID: 21156650
156 results