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Preclinical assessment of MEK1/2 inhibitors for neurofibromatosis type 2-associated schwannomas reveals differences in efficacy and drug resistance development.
Fuse MA, Dinh CT, Vitte J, Kirkpatrick J, Mindos T, Plati SK, Young JI, Huang J, Carlstedt A, Franco MC, Brnjos K, Nagamoto J, Petrilli AM, Copik AJ, Soulakova JN, Bracho O, Yan D, Mittal R, Shen R, Telischi FF, Morrison H, Giovannini M, Liu XZ, Chang LS, Fernandez-Valle C. Fuse MA, et al. Among authors: bracho o. Neuro Oncol. 2019 Mar 18;21(4):486-497. doi: 10.1093/neuonc/noz002. Neuro Oncol. 2019. PMID: 30615146 Free PMC article.
Ponatinib promotes a G1 cell-cycle arrest of merlin/NF2-deficient human schwann cells.
Petrilli AM, Garcia J, Bott M, Klingeman Plati S, Dinh CT, Bracho OR, Yan D, Zou B, Mittal R, Telischi FF, Liu XZ, Chang LS, Welling DB, Copik AJ, Fernández-Valle C. Petrilli AM, et al. Oncotarget. 2017 May 9;8(19):31666-31681. doi: 10.18632/oncotarget.15912. Oncotarget. 2017. PMID: 28427224 Free PMC article.
Combination Therapy with c-Met and Src Inhibitors Induces Caspase-Dependent Apoptosis of Merlin-Deficient Schwann Cells and Suppresses Growth of Schwannoma Cells.
Fuse MA, Plati SK, Burns SS, Dinh CT, Bracho O, Yan D, Mittal R, Shen R, Soulakova JN, Copik AJ, Liu XZ, Telischi FF, Chang LS, Franco MC, Fernandez-Valle C. Fuse MA, et al. Among authors: bracho o. Mol Cancer Ther. 2017 Nov;16(11):2387-2398. doi: 10.1158/1535-7163.MCT-17-0417. Epub 2017 Aug 3. Mol Cancer Ther. 2017. PMID: 28775147
A Xenograft Model of Vestibular Schwannoma and Hearing Loss.
Dinh CT, Bracho O, Mei C, Bas E, Fernandez-Valle C, Telischi F, Liu XZ. Dinh CT, et al. Among authors: bracho o. Otol Neurotol. 2018 Jun;39(5):e362-e369. doi: 10.1097/MAO.0000000000001766. Otol Neurotol. 2018. PMID: 29557843 Free PMC article.
Fluorescent Detection of Merlin-deficient Schwann Cells and Primary Human Vestibular Schwannoma Cells Using Sodium Fluorescein.
Perez ER, Bracho O, Ein L, Szczupak M, Monje PV, Fernandez-Valle C, Alshaiji A, Ivan M, Morcos J, Liu XZ, Hoffer M, Eshraghi A, Angeli S, Telischi F, Dinh CT. Perez ER, et al. Among authors: bracho o. Otol Neurotol. 2018 Sep;39(8):1053-1059. doi: 10.1097/MAO.0000000000001895. Otol Neurotol. 2018. PMID: 30001282 Free PMC article.
19 results