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Protective effect of lidocaine in acute cerebral ischemia induced by air embolism.
Evans DE, Kobrine AI, LeGrys DC, Bradley ME. Evans DE, et al. J Neurosurg. 1984 Feb;60(2):257-63. doi: 10.3171/jns.1984.60.2.0257. J Neurosurg. 1984. PMID: 6693953
Effect of intravenous lidocaine on experimental spinal cord injury.
Kobrine AI, Evans DE, LeGrys DC, Yaffe LJ, Bradley ME. Kobrine AI, et al. J Neurosurg. 1984 Mar;60(3):595-601. doi: 10.3171/jns.1984.60.3.0595. J Neurosurg. 1984. PMID: 6699704
Azole-resistant Aspergillus and Echinocandin-resistant Candida - What are the treatment options?
Novak AR, Bradley ME, Kiser TH, Mueller SW. Novak AR, et al. Among authors: bradley me. Curr Fungal Infect Rep. 2020 Jun;14(2):141-152. doi: 10.1007/s12281-020-00379-2. Epub 2020 Mar 26. Curr Fungal Infect Rep. 2020. PMID: 32699568
Metastatic Klebsiella pneumoniae Invasive Liver Abscess Syndrome in Denver, Colorado.
Bradley ME, Scoular SK. Bradley ME, et al. J Pharm Pract. 2019 Oct 23:897190019882867. doi: 10.1177/0897190019882867. Online ahead of print. J Pharm Pract. 2019. PMID: 31645222
Fevipiprant (QAW039), a Slowly Dissociating CRTh2 Antagonist with the Potential for Improved Clinical Efficacy.
Sykes DA, Bradley ME, Riddy DM, Willard E, Reilly J, Miah A, Bauer C, Watson SJ, Sandham DA, Dubois G, Charlton SJ. Sykes DA, et al. Among authors: bradley me. Mol Pharmacol. 2016 May;89(5):593-605. doi: 10.1124/mol.115.101832. Epub 2016 Feb 25. Mol Pharmacol. 2016. PMID: 26916831
Long Receptor Residence Time of C26 Contributes to Super Agonist Activity at the Human β2 Adrenoceptor.
Rosethorne EM, Bradley ME, Gherbi K, Sykes DA, Sattikar A, Wright JD, Renard E, Trifilieff A, Fairhurst RA, Charlton SJ. Rosethorne EM, et al. Among authors: bradley me. Mol Pharmacol. 2016 Apr;89(4):467-75. doi: 10.1124/mol.115.101253. Epub 2016 Jan 15. Mol Pharmacol. 2016. PMID: 26772612
Functional desensitization of the β 2 adrenoceptor is not dependent on agonist efficacy.
Rosethorne EM, Bradley ME, Kent TC, Charlton SJ. Rosethorne EM, et al. Among authors: bradley me. Pharmacol Res Perspect. 2015 Feb;3(1):e00101. doi: 10.1002/prp2.101. Epub 2015 Jan 5. Pharmacol Res Perspect. 2015. PMID: 25692019 Free PMC article.
Potent and efficacious inhibition of CXCR2 signaling by biparatopic nanobodies combining two distinct modes of action.
Bradley ME, Dombrecht B, Manini J, Willis J, Vlerick D, De Taeye S, Van den Heede K, Roobrouck A, Grot E, Kent TC, Laeremans T, Steffensen S, Van Heeke G, Brown Z, Charlton SJ, Cromie KD. Bradley ME, et al. Mol Pharmacol. 2015 Feb;87(2):251-62. doi: 10.1124/mol.114.094821. Epub 2014 Dec 2. Mol Pharmacol. 2015. PMID: 25468882
Investigating the molecular mechanisms through which FTY720-P causes persistent S1P1 receptor internalization.
Sykes DA, Riddy DM, Stamp C, Bradley ME, McGuiness N, Sattikar A, Guerini D, Rodrigues I, Glaenzel A, Dowling MR, Mullershausen F, Charlton SJ. Sykes DA, et al. Among authors: bradley me. Br J Pharmacol. 2014 Nov;171(21):4797-807. doi: 10.1111/bph.12620. Br J Pharmacol. 2014. PMID: 24641481 Free PMC article.
An investigation into the structure-activity relationships associated with the systematic modification of the β(2)-adrenoceptor agonist indacaterol.
Beattie D, Beer D, Bradley ME, Bruce I, Charlton SJ, Cuenoud BM, Fairhurst RA, Farr D, Fozard JR, Janus D, Rosethorne EM, Sandham DA, Sykes DA, Trifilieff A, Turner KL, Wissler E. Beattie D, et al. Among authors: bradley me. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6280-5. doi: 10.1016/j.bmcl.2012.07.096. Epub 2012 Aug 4. Bioorg Med Chem Lett. 2012. PMID: 22932315
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