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New natural product families from an environmental DNA (eDNA) gene cluster.
Brady SF, Chao CJ, Clardy J. Brady SF, et al. J Am Chem Soc. 2002 Aug 28;124(34):9968-9. doi: 10.1021/ja0268985. J Am Chem Soc. 2002. PMID: 12188643
Arixanthomycins A-C: Phylogeny-guided discovery of biologically active eDNA-derived pentangular polyphenols.
Kang HS, Brady SF. Kang HS, et al. Among authors: brady sf. ACS Chem Biol. 2014 Jun 20;9(6):1267-72. doi: 10.1021/cb500141b. Epub 2014 Apr 30. ACS Chem Biol. 2014. PMID: 24730509 Free PMC article.
Synthesis of long-chain fatty acid enol esters isolated from an environmental DNA clone.
Brady SF, Clardy J. Brady SF, et al. Org Lett. 2003 Jan 23;5(2):121-4. doi: 10.1021/ol0267681. Org Lett. 2003. PMID: 12529120
Natural products from environmental DNA hosted in Ralstonia metallidurans.
Craig JW, Chang FY, Brady SF. Craig JW, et al. Among authors: brady sf. ACS Chem Biol. 2009 Jan 16;4(1):23-8. doi: 10.1021/cb8002754. ACS Chem Biol. 2009. PMID: 19146479 Free PMC article.
Construction of soil environmental DNA cosmid libraries and screening for clones that produce biologically active small molecules.
Brady SF. Brady SF. Nat Protoc. 2007;2(5):1297-305. doi: 10.1038/nprot.2007.195. Nat Protoc. 2007. PMID: 17546026
N-acyl derivatives of arginine and tryptophan isolated from environmental DNA expressed in Escherichia coli.
Brady SF, Clardy J. Brady SF, et al. Org Lett. 2005 Aug 18;7(17):3613-6. doi: 10.1021/ol0509585. Org Lett. 2005. PMID: 16092832
Palmitoylputrescine, an antibiotic isolated from the heterologous expression of DNA extracted from bromeliad tank water.
Brady SF, Clardy J. Brady SF, et al. J Nat Prod. 2004 Aug;67(8):1283-6. doi: 10.1021/np0499766. J Nat Prod. 2004. PMID: 15332842
Long-chain N-acyltyrosine synthases from environmental DNA.
Brady SF, Chao CJ, Clardy J. Brady SF, et al. Appl Environ Microbiol. 2004 Nov;70(11):6865-70. doi: 10.1128/AEM.70.11.6865-6870.2004. Appl Environ Microbiol. 2004. PMID: 15528554 Free PMC article.
Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived type II PKS gene cluster.
Feng Z, Kim JH, Brady SF. Feng Z, et al. Among authors: brady sf. J Am Chem Soc. 2010 Sep 1;132(34):11902-3. doi: 10.1021/ja104550p. J Am Chem Soc. 2010. PMID: 20690632 Free PMC article.
Natural products from isnA-containing biosynthetic gene clusters recovered from the genomes of cultured and uncultured bacteria.
Brady SF, Bauer JD, Clarke-Pearson MF, Daniels R. Brady SF, et al. J Am Chem Soc. 2007 Oct 10;129(40):12102-3. doi: 10.1021/ja075492v. Epub 2007 Sep 19. J Am Chem Soc. 2007. PMID: 17880089 No abstract available.
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