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Biosynthesis of fungal melanins and their importance for human pathogenic fungi.
Langfelder K, Streibel M, Jahn B, Haase G, Brakhage AA. Langfelder K, et al. Fungal Genet Biol. 2003 Mar;38(2):143-58. doi: 10.1016/s1087-1845(02)00526-1. Fungal Genet Biol. 2003. PMID: 12620252 Review.
Melanin targets LC3-associated phagocytosis (LAP): A novel pathogenetic mechanism in fungal disease.
Chamilos G, Akoumianaki T, Kyrmizi I, Brakhage A, Beauvais A, Latge JP. Chamilos G, et al. Autophagy. 2016 May 3;12(5):888-9. doi: 10.1080/15548627.2016.1157242. Epub 2016 Mar 30. Autophagy. 2016. PMID: 27028978 Free PMC article. Review.
Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper.
Meyer V, Andersen MR, Brakhage AA, Braus GH, Caddick MX, Cairns TC, de Vries RP, Haarmann T, Hansen K, Hertz-Fowler C, Krappmann S, Mortensen UH, Peñalva MA, Ram AFJ, Head RM. Meyer V, et al. Fungal Biol Biotechnol. 2016 Aug 31;3:6. doi: 10.1186/s40694-016-0024-8. eCollection 2016. Fungal Biol Biotechnol. 2016. PMID: 28955465 Free PMC article.
Recreation of in-host acquired single nucleotide polymorphisms by CRISPR-Cas9 reveals an uncharacterised gene playing a role in Aspergillus fumigatus azole resistance via a non-cyp51A mediated resistance mechanism.
Ballard E, Weber J, Melchers WJG, Tammireddy S, Whitfield PD, Brakhage AA, Brown AJP, Verweij PE, Warris A. Ballard E, et al. Fungal Genet Biol. 2019 Sep;130:98-106. doi: 10.1016/j.fgb.2019.05.005. Epub 2019 May 23. Fungal Genet Biol. 2019. PMID: 31128273 Free PMC article.
Analysis of the regulation, expression, and localisation of the isocitrate lyase from Aspergillus fumigatus, a potential target for antifungal drug development.
Ebel F, Schwienbacher M, Beyer J, Heesemann J, Brakhage AA, Brock M. Ebel F, et al. Fungal Genet Biol. 2006 Jul;43(7):476-89. doi: 10.1016/j.fgb.2006.01.015. Fungal Genet Biol. 2006. PMID: 16603391
Regulation and Role of Fungal Secondary Metabolites.
Macheleidt J, Mattern DJ, Fischer J, Netzker T, Weber J, Schroeckh V, Valiante V, Brakhage AA. Macheleidt J, et al. Annu Rev Genet. 2016 Nov 23;50:371-392. doi: 10.1146/annurev-genet-120215-035203. Epub 2016 Oct 5. Annu Rev Genet. 2016. PMID: 27732794 Review.
Regulation of penicillin biosynthesis in filamentous fungi.
Brakhage AA, Spröte P, Al-Abdallah Q, Gehrke A, Plattner H, Tüncher A. Brakhage AA, et al. Adv Biochem Eng Biotechnol. 2004;88:45-90. doi: 10.1007/b99257. Adv Biochem Eng Biotechnol. 2004. PMID: 15719552 Review.
Genome mining reveals the presence of a conserved gene cluster for the biosynthesis of ergot alkaloid precursors in the fungal family Arthrodermataceae.
Wallwey C, Heddergott C, Xie X, Brakhage AA, Li SM. Wallwey C, et al. Microbiology (Reading). 2012 Jun;158(Pt 6):1634-1644. doi: 10.1099/mic.0.056796-0. Epub 2012 Mar 8. Microbiology (Reading). 2012. PMID: 22403186
A single subunit of a heterotrimeric CCAAT-binding complex carries a nuclear localization signal: piggy back transport of the pre-assembled complex to the nucleus.
Steidl S, Tüncher A, Goda H, Guder C, Papadopoulou N, Kobayashi T, Tsukagoshi N, Kato M, Brakhage AA. Steidl S, et al. J Mol Biol. 2004 Sep 10;342(2):515-24. doi: 10.1016/j.jmb.2004.07.011. J Mol Biol. 2004. PMID: 15327951
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