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Tumor-targeting domains for chimeric antigen receptor T cells.
Bezverbnaya K, Mathews A, Sidhu J, Helsen CW, Bramson JL. Bezverbnaya K, et al. Among authors: bramson jl. Immunotherapy. 2017 Jan;9(1):33-46. doi: 10.2217/imt-2016-0103. Immunotherapy. 2017. PMID: 28000526 Review.
AMPK β1 reduces tumor progression and improves survival in p53 null mice.
Houde VP, Donzelli S, Sacconi A, Galic S, Hammill JA, Bramson JL, Foster RA, Tsakiridis T, Kemp BE, Grasso G, Blandino G, Muti P, Steinberg GR. Houde VP, et al. Among authors: bramson jl. Mol Oncol. 2017 Sep;11(9):1143-1155. doi: 10.1002/1878-0261.12079. Epub 2017 Jun 28. Mol Oncol. 2017. PMID: 28544264 Free PMC article.
The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity.
Helsen CW, Hammill JA, Lau VWC, Mwawasi KA, Afsahi A, Bezverbnaya K, Newhook L, Hayes DL, Aarts C, Bojovic B, Denisova GF, Kwiecien JM, Brain I, Derocher H, Milne K, Nelson BH, Bramson JL. Helsen CW, et al. Among authors: bramson jl. Nat Commun. 2018 Aug 3;9(1):3049. doi: 10.1038/s41467-018-05395-y. Nat Commun. 2018. PMID: 30076299 Free PMC article.
162 results