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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1941 1
1946 1
1947 1
1948 2
1949 5
1950 1
1951 1
1952 5
1953 4
1954 6
1955 8
1956 2
1958 1
1959 1
1960 1
1961 9
1962 5
1963 9
1964 7
1965 12
1966 18
1967 20
1968 30
1969 21
1970 28
1971 34
1972 32
1973 37
1974 40
1975 50
1976 72
1977 62
1978 94
1979 119
1980 118
1981 119
1982 168
1983 175
1984 180
1985 206
1986 191
1987 183
1988 210
1989 206
1990 195
1991 216
1992 188
1993 165
1994 170
1995 191
1996 181
1997 170
1998 199
1999 174
2000 228
2001 204
2002 190
2003 230
2004 251
2005 247
2006 274
2007 258
2008 246
2009 264
2010 302
2011 347
2012 427
2013 434
2014 432
2015 459
2016 535
2017 551
2018 603
2019 678
2020 754
2021 807
2022 806
2023 795
2024 932
2025 151

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14,437 results

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Page 1
Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer.
Sivanand S, Vander Heiden MG. Sivanand S, et al. Cancer Cell. 2020 Feb 10;37(2):147-156. doi: 10.1016/j.ccell.2019.12.011. Cancer Cell. 2020. PMID: 32049045 Free PMC article. Review.
Amino acid metabolism is deregulated in many cancers, with changes in branched-chain amino acid metabolism specifically affecting cancer cell state as well as systemic metabolism in individuals with malignancy. This review highlights key concepts surrounding the cur …
Amino acid metabolism is deregulated in many cancers, with changes in branched-chain amino acid metabolism specifically affect …
Branched-Chain Amino Acids.
Yamamoto K, Tsuchisaka A, Yukawa H. Yamamoto K, et al. Adv Biochem Eng Biotechnol. 2017;159:103-128. doi: 10.1007/10_2016_28. Adv Biochem Eng Biotechnol. 2017. PMID: 27872960 Review.
Branched-chain amino acids (BCAAs), viz., L-isoleucine, L-leucine, and L-valine, are essential amino acids that cannot be synthesized in higher organisms and are important nutrition for humans as well as livestock. ...
Branched-chain amino acids (BCAAs), viz., L-isoleucine, L-leucine, and L-valine, are essential amino acids that cannot be synt
Branched-Chain Amino Acid Metabolism in the Failing Heart.
Karwi QG, Lopaschuk GD. Karwi QG, et al. Cardiovasc Drugs Ther. 2023 Apr;37(2):413-420. doi: 10.1007/s10557-022-07320-4. Epub 2022 Feb 12. Cardiovasc Drugs Ther. 2023. PMID: 35150384 Review.
Branched-chain amino acids (BCAAs) are essential amino acids which have critical roles in protein synthesis and energy metabolism in the body. ...Plasma and myocardial levels of BCAA and their metabolites, namely branched-chain keto acids (BCKAs), are
Branched-chain amino acids (BCAAs) are essential amino acids which have critical roles in protein synthesis and energy metabol
Research progress on branched-chain amino acid aminotransferases.
Chen C, Naveed H, Chen K. Chen C, et al. Front Genet. 2023 Nov 6;14:1233669. doi: 10.3389/fgene.2023.1233669. eCollection 2023. Front Genet. 2023. PMID: 38028625 Free PMC article. Review.
Branched-chain amino acid aminotransferases, widely present in natural organisms, catalyze bidirectional amino transfer between branched-chain amino acids and branched-chain alpha-ketoacids in cells. Branched-chain amino aci
Branched-chain amino acid aminotransferases, widely present in natural organisms, catalyze bidirectional amino transfer betwee
The Critical Role of the Branched Chain Amino Acids (BCAAs) Catabolism-Regulating Enzymes, Branched-Chain Aminotransferase (BCAT) and Branched-Chain alpha-Keto Acid Dehydrogenase (BCKD), in Human Pathophysiology.
Dimou A, Tsimihodimos V, Bairaktari E. Dimou A, et al. Int J Mol Sci. 2022 Apr 5;23(7):4022. doi: 10.3390/ijms23074022. Int J Mol Sci. 2022. PMID: 35409380 Free PMC article. Review.
Branched chain amino acids (BCAAs), leucine, isoleucine and valine, are essential amino acids widely studied for their crucial role in the regulation of protein synthesis mainly through the activation of the mTOR signaling pathway and their emerging recognition as p
Branched chain amino acids (BCAAs), leucine, isoleucine and valine, are essential amino acids widely studied for their crucial
Branched-Chain Amino Acids and Brain Metabolism.
Sperringer JE, Addington A, Hutson SM. Sperringer JE, et al. Neurochem Res. 2017 Jun;42(6):1697-1709. doi: 10.1007/s11064-017-2261-5. Epub 2017 Apr 18. Neurochem Res. 2017. PMID: 28417264 Review.
This review aims to provide a historical reference of branched-chain amino acid (BCAA) metabolism and provide a link between peripheral and central nervous system (CNS) metabolism of BCAAs. ...MSUD is the most prolific disease associated with BCAA metabolism, affect …
This review aims to provide a historical reference of branched-chain amino acid (BCAA) metabolism and provide a link between p …
Branched Chain Amino Acids in Metabolic Disease.
Arany Z, Neinast M. Arany Z, et al. Curr Diab Rep. 2018 Aug 15;18(10):76. doi: 10.1007/s11892-018-1048-7. Curr Diab Rep. 2018. PMID: 30112615 Review.
PURPOSE OF REVIEW: Elevations in circulating branched chain amino acids (BCAAs) have gained attention as potential contributors to the development of insulin resistance and diabetes. ...
PURPOSE OF REVIEW: Elevations in circulating branched chain amino acids (BCAAs) have gained attention as potential contributor …
Potential roles of branched-chain amino acids in neurodegeneration.
Yoo HS, Shanmugalingam U, Smith PD. Yoo HS, et al. Nutrition. 2022 Nov-Dec;103-104:111762. doi: 10.1016/j.nut.2022.111762. Epub 2022 Jun 3. Nutrition. 2022. PMID: 35843039 Review.
Although the common underlying cause of these neurodegenerative processes has yet to be identified, accumulating evidence suggests that branched-chain amino acids (BCAAs) could be involved. BCAAs have been shown to not only influence the central levels of neurotrans …
Although the common underlying cause of these neurodegenerative processes has yet to be identified, accumulating evidence suggests that b
Immunometabolism - The Role of Branched-Chain Amino Acids.
Yahsi B, Gunaydin G. Yahsi B, et al. Front Immunol. 2022 Jun 23;13:886822. doi: 10.3389/fimmu.2022.886822. eCollection 2022. Front Immunol. 2022. PMID: 35812393 Free PMC article. Review.
Recently, an association between Tregs and isoleucine, which represents one type of branched-chain amino acids (BCAAs), has been demonstrated. The presence of isoleucine seems to affect majorly Tregs, rather than conventional T cells. ...
Recently, an association between Tregs and isoleucine, which represents one type of branched-chain amino acids (BCAAs), has be …
14,437 results
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