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Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes.
Gram DX, Ahrén B, Nagy I, Olsen UB, Brand CL, Sundler F, Tabanera R, Svendsen O, Carr RD, Santha P, Wierup N, Hansen AJ. Gram DX, et al. Among authors: brand cl. Eur J Neurosci. 2007 Jan;25(1):213-23. doi: 10.1111/j.1460-9568.2006.05261.x. Eur J Neurosci. 2007. PMID: 17241282
Sensory nerve desensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in Zucker Diabetic Fatty rats and is associated with reduced plasma activity of dipeptidyl peptidase IV.
Gram DX, Hansen AJ, Deacon CF, Brand CL, Ribel U, Wilken M, Carr RD, Svendsen O, Ahrén B. Gram DX, et al. Among authors: brand cl. Eur J Pharmacol. 2005 Feb 21;509(2-3):211-7. doi: 10.1016/j.ejphar.2004.12.039. Eur J Pharmacol. 2005. PMID: 15733558
133 results