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Bcr and Raf form a complex in vivo via 14-3-3 proteins.
Braselmann S, McCormick F. Braselmann S, et al. EMBO J. 1995 Oct 2;14(19):4839-48. EMBO J. 1995. PMID: 7588613 Free PMC article.
Signalling enzymes: bursting with potential.
Braselmann S, Palmer TM, Cook SJ. Braselmann S, et al. Curr Biol. 1997 Aug 1;7(8):R470-3. doi: 10.1016/s0960-9822(06)00239-9. Curr Biol. 1997. PMID: 9259544 Free article. Review.
Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor.
Bergers G, Reikerstorfer A, Braselmann S, Graninger P, Busslinger M. Bergers G, et al. Among authors: braselmann s. EMBO J. 1994 Mar 1;13(5):1176-88. EMBO J. 1994. PMID: 8131748 Free PMC article.
R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation.
Braselmann S, Taylor V, Zhao H, Wang S, Sylvain C, Baluom M, Qu K, Herlaar E, Lau A, Young C, Wong BR, Lovell S, Sun T, Park G, Argade A, Jurcevic S, Pine P, Singh R, Grossbard EB, Payan DG, Masuda ES. Braselmann S, et al. J Pharmacol Exp Ther. 2006 Dec;319(3):998-1008. doi: 10.1124/jpet.106.109058. Epub 2006 Aug 31. J Pharmacol Exp Ther. 2006. PMID: 16946104 Clinical Trial.
Identification of the Syk kinase inhibitor R112 by a human mast cell screen.
Rossi AB, Herlaar E, Braselmann S, Huynh S, Taylor V, Frances R, Issakani SD, Argade A, Singh R, Payan DG, Masuda ES. Rossi AB, et al. Among authors: braselmann s. J Allergy Clin Immunol. 2006 Sep;118(3):749-55. doi: 10.1016/j.jaci.2006.05.023. Epub 2006 Jul 28. J Allergy Clin Immunol. 2006. PMID: 16950297
A selective transcriptional induction system for mammalian cells based on Gal4-estrogen receptor fusion proteins.
Braselmann S, Graninger P, Busslinger M. Braselmann S, et al. Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):1657-61. doi: 10.1073/pnas.90.5.1657. Proc Natl Acad Sci U S A. 1993. PMID: 8446579 Free PMC article.
Identification of Fos target genes by the use of selective induction systems.
Braselmann S, Bergers G, Wrighton C, Graninger P, Superti-Furga G, Busslinger M. Braselmann S, et al. J Cell Sci Suppl. 1992;16:97-109. doi: 10.1242/jcs.1992.supplement_16.12. J Cell Sci Suppl. 1992. PMID: 1297655 Review.
Transcriptional activation of the fra-1 gene by AP-1 is mediated by regulatory sequences in the first intron.
Bergers G, Graninger P, Braselmann S, Wrighton C, Busslinger M. Bergers G, et al. Among authors: braselmann s. Mol Cell Biol. 1995 Jul;15(7):3748-58. doi: 10.1128/mcb.15.7.3748. Mol Cell Biol. 1995. PMID: 7791782 Free PMC article.
Design, synthesis of diaminopyrimidine inhibitors targeting IgE- and IgG-mediated activation of Fc receptor signaling.
Argade A, Bhamidipati S, Li H, Sylvain C, Clough J, Carroll D, Keim H, Braselmann S, Taylor V, Zhao H, Herlaar E, Issakani SD, Wong BR, Masuda ES, Payan DG, Singh R. Argade A, et al. Among authors: braselmann s. Bioorg Med Chem Lett. 2015;25(10):2122-8. doi: 10.1016/j.bmcl.2015.03.072. Epub 2015 Apr 1. Bioorg Med Chem Lett. 2015. PMID: 25891105
JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 mutant PL/J mice.
Chang BY, Zhao F, He X, Ren H, Braselmann S, Taylor V, Wicks J, Payan DG, Grossbard EB, Pine PR, Bullard DC. Chang BY, et al. Among authors: braselmann s. J Immunol. 2009 Aug 1;183(3):2183-92. doi: 10.4049/jimmunol.0804063. Epub 2009 Jul 13. J Immunol. 2009. PMID: 19596999 Free article.
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