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Remnant particles are the major determinant of an increased intima media thickness in patients with familial combined hyperlipidemia (FCH).
ter Avest E, Holewijn S, Bredie SJ, Stalenhoef AF, de Graaf J. ter Avest E, et al. Among authors: bredie sj. Atherosclerosis. 2007 Mar;191(1):220-6. doi: 10.1016/j.atherosclerosis.2006.03.025. Epub 2006 May 4. Atherosclerosis. 2007. PMID: 16677651
Comparison of gemfibrozil versus simvastatin in familial combined hyperlipidemia and effects on apolipoprotein-B-containing lipoproteins, low-density lipoprotein subfraction profile, and low-density lipoprotein oxidizability.
Bredie SJ, de Bruin TW, Demacker PN, Kastelein JJ, Stalenhoef AF. Bredie SJ, et al. Am J Cardiol. 1995 Feb 15;75(5):348-53. doi: 10.1016/s0002-9149(99)80552-9. Am J Cardiol. 1995. PMID: 7856526 Clinical Trial.
Inherited susceptibility determines the distribution of dense low-density lipoprotein subfraction profiles in familial combined hyperlipidemia.
Bredie SJ, Kiemeney LA, de Haan AF, Demacker PN, Stalenhoef AF. Bredie SJ, et al. Am J Hum Genet. 1996 Apr;58(4):812-22. Am J Hum Genet. 1996. PMID: 8644746 Free PMC article.
The lipoprotein lipase (Asn291-->Ser) mutation is associated with elevated lipid levels in families with familial combined hyperlipidaemia.
Hoffer MJ, Bredie SJ, Boomsma DI, Reymer PW, Kastelein JJ, de Knijff P, Demacker PN, Stalenhoef AF, Havekes LM, Frants RR. Hoffer MJ, et al. Among authors: bredie sj. Atherosclerosis. 1996 Jan 26;119(2):159-67. doi: 10.1016/0021-9150(95)05641-6. Atherosclerosis. 1996. PMID: 8808493
Effects of gemfibrozil or simvastatin on apolipoprotein-B-containing lipoproteins, apolipoprotein-CIII and lipoprotein(a) in familial combined hyperlipidaemia.
Bredie SJ, Westerveld HT, Knipscheer HC, de Bruin TW, Kastelein JJ, Stalenhoef AF. Bredie SJ, et al. Neth J Med. 1996 Aug;49(2):59-67. doi: 10.1016/0300-2977(96)00015-0. Neth J Med. 1996. PMID: 8824106 Clinical Trial.
Apolipoprotein E polymorphism influences lipid phenotypic expression, but not the low density lipoprotein subfraction distribution in familial combined hyperlipidemia.
Bredie SJ, Vogelaar JM, Demacker PN, Stalenhoef AF. Bredie SJ, et al. Atherosclerosis. 1996 Oct 25;126(2):313-24. doi: 10.1016/0021-9150(96)05924-2. Atherosclerosis. 1996. PMID: 8902157
The redox status of coenzyme Q10 in total LDL as an indicator of in vivo oxidative modification. Studies on subjects with familial combined hyperlipidemia.
de Rijke YB, Bredie SJ, Demacker PN, Vogelaar JM, Hak-Lemmers HL, Stalenhoef AF. de Rijke YB, et al. Among authors: bredie sj. Arterioscler Thromb Vasc Biol. 1997 Jan;17(1):127-33. doi: 10.1161/01.atv.17.1.127. Arterioscler Thromb Vasc Biol. 1997. PMID: 9012647
Segregation analysis of plasma apolipoprotein B levels in familial combined hyperlipidemia.
Bredie SJ, van Drongelen J, Kiemeney LA, Demacker PN, Beaty TH, Stalenhoef AF. Bredie SJ, et al. Arterioscler Thromb Vasc Biol. 1997 May;17(5):834-40. doi: 10.1161/01.atv.17.5.834. Arterioscler Thromb Vasc Biol. 1997. PMID: 9157945
Nonobese patients with familial combined hyperlipidemia are insulin resistant compared with their nonaffected relatives.
Bredie SJ, Tack CJ, Smits P, Stalenhoef AF. Bredie SJ, et al. Arterioscler Thromb Vasc Biol. 1997 Jul;17(7):1465-71. Arterioscler Thromb Vasc Biol. 1997. PMID: 9261281
Metabolic and genetic aspects of familial combined hyperlipidaemia with emphasis on low-density lipoprotein heterogeneity.
Bredie SJ, Demacker PN, Stalenhoef AF. Bredie SJ, et al. Eur J Clin Invest. 1997 Oct;27(10):802-11. doi: 10.1046/j.1365-2362.1997.1850734.x. Eur J Clin Invest. 1997. PMID: 9373757 Review. No abstract available.
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