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Creeping baselines and adaptive resistance to antibiotics.
Fernández L, Breidenstein EB, Hancock RE. Fernández L, et al. Drug Resist Updat. 2011 Feb;14(1):1-21. doi: 10.1016/j.drup.2011.01.001. Epub 2011 Feb 1. Drug Resist Updat. 2011. PMID: 21288762 Review.
The Lon protease is essential for full virulence in Pseudomonas aeruginosa.
Breidenstein EB, Janot L, Strehmel J, Fernandez L, Taylor PK, Kukavica-Ibrulj I, Gellatly SL, Levesque RC, Overhage J, Hancock RE. Breidenstein EB, et al. PLoS One. 2012;7(11):e49123. doi: 10.1371/journal.pone.0049123. Epub 2012 Nov 7. PLoS One. 2012. PMID: 23145092 Free PMC article.
Involvement of the lon protease in the SOS response triggered by ciprofloxacin in Pseudomonas aeruginosa PAO1.
Breidenstein EB, Bains M, Hancock RE. Breidenstein EB, et al. Antimicrob Agents Chemother. 2012 Jun;56(6):2879-87. doi: 10.1128/AAC.06014-11. Epub 2012 Mar 26. Antimicrob Agents Chemother. 2012. PMID: 22450976 Free PMC article.
Inhibition of bacterial biofilm formation and swarming motility by a small synthetic cationic peptide.
de la Fuente-Núñez C, Korolik V, Bains M, Nguyen U, Breidenstein EB, Horsman S, Lewenza S, Burrows L, Hancock RE. de la Fuente-Núñez C, et al. Among authors: breidenstein eb. Antimicrob Agents Chemother. 2012 May;56(5):2696-704. doi: 10.1128/AAC.00064-12. Epub 2012 Feb 21. Antimicrob Agents Chemother. 2012. PMID: 22354291 Free PMC article.
Role of intracellular proteases in the antibiotic resistance, motility, and biofilm formation of Pseudomonas aeruginosa.
Fernández L, Breidenstein EB, Song D, Hancock RE. Fernández L, et al. Among authors: breidenstein eb. Antimicrob Agents Chemother. 2012 Feb;56(2):1128-32. doi: 10.1128/AAC.05336-11. Epub 2011 Nov 28. Antimicrob Agents Chemother. 2012. PMID: 22123702 Free PMC article.
Pseudomonas aeruginosa: all roads lead to resistance.
Breidenstein EB, de la Fuente-Núñez C, Hancock RE. Breidenstein EB, et al. Trends Microbiol. 2011 Aug;19(8):419-26. doi: 10.1016/j.tim.2011.04.005. Epub 2011 Jun 12. Trends Microbiol. 2011. PMID: 21664819 Review.
Complex ciprofloxacin resistome revealed by screening a Pseudomonas aeruginosa mutant library for altered susceptibility.
Breidenstein EB, Khaira BK, Wiegand I, Overhage J, Hancock RE. Breidenstein EB, et al. Antimicrob Agents Chemother. 2008 Dec;52(12):4486-91. doi: 10.1128/AAC.00222-08. Epub 2008 Sep 29. Antimicrob Agents Chemother. 2008. PMID: 18824609 Free PMC article.
Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin.
Brazas MD, Breidenstein EB, Overhage J, Hancock RE. Brazas MD, et al. Antimicrob Agents Chemother. 2007 Dec;51(12):4276-83. doi: 10.1128/AAC.00830-07. Epub 2007 Sep 24. Antimicrob Agents Chemother. 2007. PMID: 17893152 Free PMC article.
Mutator genes giving rise to decreased antibiotic susceptibility in Pseudomonas aeruginosa.
Wiegand I, Marr AK, Breidenstein EB, Schurek KN, Taylor P, Hancock RE. Wiegand I, et al. Antimicrob Agents Chemother. 2008 Oct;52(10):3810-3. doi: 10.1128/AAC.00233-08. Epub 2008 Jul 28. Antimicrob Agents Chemother. 2008. PMID: 18663021 Free PMC article.
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