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19 results
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One gene, two paracellular ion channels-claudin-10 in the kidney.
Milatz S, Breiderhoff T. Milatz S, et al. Among authors: breiderhoff t. Pflugers Arch. 2017 Jan;469(1):115-121. doi: 10.1007/s00424-016-1921-7. Epub 2016 Dec 10. Pflugers Arch. 2017. PMID: 27942952 Review.
Altered paracellular cation permeability due to a rare CLDN10B variant causes anhidrosis and kidney damage.
Klar J, Piontek J, Milatz S, Tariq M, Jameel M, Breiderhoff T, Schuster J, Fatima A, Asif M, Sher M, Mäbert K, Fromm A, Baig SM, Günzel D, Dahl N. Klar J, et al. Among authors: breiderhoff t. PLoS Genet. 2017 Jul 7;13(7):e1006897. doi: 10.1371/journal.pgen.1006897. eCollection 2017 Jul. PLoS Genet. 2017. PMID: 28686597 Free PMC article.
Deletion of claudin-10 rescues claudin-16-deficient mice from hypomagnesemia and hypercalciuria.
Breiderhoff T, Himmerkus N, Drewell H, Plain A, Günzel D, Mutig K, Willnow TE, Müller D, Bleich M. Breiderhoff T, et al. Kidney Int. 2018 Mar;93(3):580-588. doi: 10.1016/j.kint.2017.08.029. Epub 2017 Nov 10. Kidney Int. 2018. PMID: 29129401
Mosaic expression of claudins in thick ascending limbs of Henle results in spatial separation of paracellular Na+ and Mg2+ transport.
Milatz S, Himmerkus N, Wulfmeyer VC, Drewell H, Mutig K, Hou J, Breiderhoff T, Müller D, Fromm M, Bleich M, Günzel D. Milatz S, et al. Among authors: breiderhoff t. Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):E219-E227. doi: 10.1073/pnas.1611684114. Epub 2016 Dec 27. Proc Natl Acad Sci U S A. 2017. PMID: 28028216 Free PMC article.
Claudin-16 Deficiency Impairs Tight Junction Function in Ameloblasts, Leading to Abnormal Enamel Formation.
Bardet C, Courson F, Wu Y, Khaddam M, Salmon B, Ribes S, Thumfart J, Yamaguti PM, Rochefort GY, Figueres ML, Breiderhoff T, Garcia-Castaño A, Vallée B, Le Denmat D, Baroukh B, Guilbert T, Schmitt A, Massé JM, Bazin D, Lorenz G, Morawietz M, Hou J, Carvalho-Lobato P, Manzanares MC, Fricain JC, Talmud D, Demontis R, Neves F, Zenaty D, Berdal A, Kiesow A, Petzold M, Menashi S, Linglart A, Acevedo AC, Vargas-Poussou R, Müller D, Houillier P, Chaussain C. Bardet C, et al. Among authors: breiderhoff t. J Bone Miner Res. 2016 Mar;31(3):498-513. doi: 10.1002/jbmr.2726. Epub 2015 Oct 20. J Bone Miner Res. 2016. PMID: 26426912 Free article.
Targeted deletion of murine Cldn16 identifies extra- and intrarenal compensatory mechanisms of Ca2+ and Mg2+ wasting.
Will C, Breiderhoff T, Thumfart J, Stuiver M, Kopplin K, Sommer K, Günzel D, Querfeld U, Meij IC, Shan Q, Bleich M, Willnow TE, Müller D. Will C, et al. Among authors: breiderhoff t. Am J Physiol Renal Physiol. 2010 May;298(5):F1152-61. doi: 10.1152/ajprenal.00499.2009. Epub 2010 Feb 10. Am J Physiol Renal Physiol. 2010. PMID: 20147368
Deletion of claudin-10 (Cldn10) in the thick ascending limb impairs paracellular sodium permeability and leads to hypermagnesemia and nephrocalcinosis.
Breiderhoff T, Himmerkus N, Stuiver M, Mutig K, Will C, Meij IC, Bachmann S, Bleich M, Willnow TE, Müller D. Breiderhoff T, et al. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14241-6. doi: 10.1073/pnas.1203834109. Epub 2012 Aug 13. Proc Natl Acad Sci U S A. 2012. PMID: 22891322 Free PMC article.
Claudin Loss-of-Function Disrupts Tight Junctions and Impairs Amelogenesis.
Bardet C, Ribes S, Wu Y, Diallo MT, Salmon B, Breiderhoff T, Houillier P, Müller D, Chaussain C. Bardet C, et al. Among authors: breiderhoff t. Front Physiol. 2017 May 24;8:326. doi: 10.3389/fphys.2017.00326. eCollection 2017. Front Physiol. 2017. PMID: 28596736 Free PMC article.
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Andersen OM, Reiche J, Schmidt V, Gotthardt M, Spoelgen R, Behlke J, von Arnim CA, Breiderhoff T, Jansen P, Wu X, Bales KR, Cappai R, Masters CL, Gliemann J, Mufson EJ, Hyman BT, Paul SM, Nykjaer A, Willnow TE. Andersen OM, et al. Among authors: breiderhoff t. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13461-6. doi: 10.1073/pnas.0503689102. Epub 2005 Sep 7. Proc Natl Acad Sci U S A. 2005. PMID: 16174740 Free PMC article.
Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
Giménez-Mascarell P, Oyenarte I, Hardy S, Breiderhoff T, Stuiver M, Kostantin E, Diercks T, Pey AL, Ereño-Orbea J, Martínez-Chantar ML, Khalaf-Nazzal R, Claverie-Martin F, Müller D, Tremblay ML, Martínez-Cruz LA. Giménez-Mascarell P, et al. Among authors: breiderhoff t. J Biol Chem. 2017 Jan 20;292(3):786-801. doi: 10.1074/jbc.M116.759944. Epub 2016 Nov 29. J Biol Chem. 2017. PMID: 27899452 Free PMC article.
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