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Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy.
Oshima N, Ishida R, Kishimoto S, Beebe K, Brender JR, Yamamoto K, Urban D, Rai G, Johnson MS, Benavides G, Squadrito GL, Crooks D, Jackson J, Joshi A, Mott BT, Shrimp JH, Moses MA, Lee MJ, Yuno A, Lee TD, Hu X, Anderson T, Kusewitt D, Hathaway HH, Jadhav A, Picard D, Trepel JB, Mitchell JB, Stott GM, Moore W, Simeonov A, Sklar LA, Norenberg JP, Linehan WM, Maloney DJ, Dang CV, Waterson AG, Hall M, Darley-Usmar VM, Krishna MC, Neckers LM. Oshima N, et al. Among authors: brender jr. Cell Rep. 2020 Feb 11;30(6):1798-1810.e4. doi: 10.1016/j.celrep.2020.01.039. Cell Rep. 2020. PMID: 32049011 Free PMC article.
Multimodality Imaging Identifies Distinct Metabolic Profiles In Vitro and In Vivo.
Neveu MA, De Preter G, Marchand V, Bol A, Brender JR, Saito K, Kishimoto S, Porporato PE, Sonveaux P, Grégoire V, Feron O, Jordan BF, Krishna MC, Gallez B. Neveu MA, et al. Among authors: brender jr. Neoplasia. 2016 Dec;18(12):742-752. doi: 10.1016/j.neo.2016.10.010. Epub 2016 Nov 24. Neoplasia. 2016. PMID: 27889643 Free PMC article.
Synthesis and evaluation of 13C-labeled 5-5-dimethyl-1-pyrroline-N-oxide aimed at in vivo detection of reactive oxygen species using hyperpolarized 13C-MRI.
Saito K, Sail D, Yamamoto K, Matsumoto S, Blackman B, Kishimoto S, Brender JR, Swenson RE, Mitchell JB, Krishna MC. Saito K, et al. Among authors: brender jr. Free Radic Biol Med. 2019 Feb 1;131:18-26. doi: 10.1016/j.freeradbiomed.2018.11.013. Epub 2018 Nov 22. Free Radic Biol Med. 2019. PMID: 30471347 Free PMC article.
Imaging of glucose metabolism by 13C-MRI distinguishes pancreatic cancer subtypes in mice.
Kishimoto S, Brender JR, Crooks DR, Matsumoto S, Seki T, Oshima N, Merkle H, Lin P, Reed G, Chen AP, Ardenkjaer-Larsen JH, Munasinghe J, Saito K, Yamamoto K, Choyke PL, Mitchell J, Lane AN, Fan TW, Linehan WM, Krishna MC. Kishimoto S, et al. Among authors: brender jr. Elife. 2019 Aug 13;8:e46312. doi: 10.7554/eLife.46312. Elife. 2019. PMID: 31408004 Free PMC article.
Molecular Imaging of the Tumor Microenvironment Reveals the Relationship between Tumor Oxygenation, Glucose Uptake, and Glycolysis in Pancreatic Ductal Adenocarcinoma.
Yamamoto K, Brender JR, Seki T, Kishimoto S, Oshima N, Choudhuri R, Adler SS, Jagoda EM, Saito K, Devasahayam N, Choyke PL, Mitchell JB, Krishna MC. Yamamoto K, et al. Among authors: brender jr. Cancer Res. 2020 Jun 1;80(11):2087-2093. doi: 10.1158/0008-5472.CAN-19-0928. Epub 2020 Apr 3. Cancer Res. 2020. PMID: 32245793 Free PMC article.
Tensor image enhancement and optimal multichannel receiver combination analyses for human hyperpolarized 13 C MRSI.
Chen HY, Autry AW, Brender JR, Kishimoto S, Krishna MC, Vareth M, Bok RA, Reed GD, Carvajal L, Gordon JW, van Criekinge M, Korenchan DE, Chen AP, Xu D, Li Y, Chang SM, Kurhanewicz J, Larson PEZ, Vigneron DB. Chen HY, et al. Among authors: brender jr. Magn Reson Med. 2020 Dec;84(6):3351-3365. doi: 10.1002/mrm.28328. Epub 2020 Jun 5. Magn Reson Med. 2020. PMID: 32501614 Free PMC article.
84 results