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Hepatic stellate cells as a target for the treatment of liver fibrosis.
Bataller R, Brenner DA. Bataller R, et al. Among authors: brenner da. Semin Liver Dis. 2001 Aug;21(3):437-51. doi: 10.1055/s-2001-17558. Semin Liver Dis. 2001. PMID: 11586471 Review.
Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype.
Schnabl B, Purbeck CA, Choi YH, Hagedorn CH, Brenner D. Schnabl B, et al. Among authors: brenner d. Hepatology. 2003 Mar;37(3):653-64. doi: 10.1053/jhep.2003.50097. Hepatology. 2003. PMID: 12601363
The role of gut-derived bacterial toxins and free radicals in alcohol-induced liver injury.
Thurman RG, Bradford BU, Iimuro Y, Knecht KT, Arteel GE, Yin M, Connor HD, Wall C, Raleigh JA, Frankenberg MV, Adachi Y, Forman DT, Brenner D, Kadiiska M, Mason RP. Thurman RG, et al. Among authors: brenner d. J Gastroenterol Hepatol. 1998 Sep;13 Suppl:S39-50. J Gastroenterol Hepatol. 1998. PMID: 9792033 Review.
The glutathione precursor L-2-oxothiazolidine-4-carboxylic acid protects against liver injury due to chronic enteral ethanol exposure in the rat.
Iimuro Y, Bradford BU, Yamashina S, Rusyn I, Nakagami M, Enomoto N, Kono H, Frey W, Forman D, Brenner D, Thurman RG. Iimuro Y, et al. Among authors: brenner d. Hepatology. 2000 Feb;31(2):391-8. doi: 10.1002/hep.510310219. Hepatology. 2000. PMID: 10655262
Hepatic stellate cells primed with cytokines upregulate inflammation in response to peptidoglycan or lipoteichoic acid.
Paik YH, Lee KS, Lee HJ, Yang KM, Lee SJ, Lee DK, Han KH, Chon CY, Lee SI, Moon YM, Brenner DA. Paik YH, et al. Among authors: brenner da. Lab Invest. 2006 Jul;86(7):676-86. doi: 10.1038/labinvest.3700422. Epub 2006 Apr 17. Lab Invest. 2006. PMID: 16619004
Norepinephrine induces calcium spikes and proinflammatory actions in human hepatic stellate cells.
Sancho-Bru P, Bataller R, Colmenero J, Gasull X, Moreno M, Arroyo V, Brenner DA, Ginès P. Sancho-Bru P, et al. Among authors: brenner da. Am J Physiol Gastrointest Liver Physiol. 2006 Nov;291(5):G877-84. doi: 10.1152/ajpgi.00537.2005. Epub 2006 Jun 15. Am J Physiol Gastrointest Liver Physiol. 2006. PMID: 16782692
NF-kappaB activation in Kupffer cells after partial hepatectomy.
Yang L, Magness ST, Bataller R, Rippe RA, Brenner DA. Yang L, et al. Among authors: brenner da. Am J Physiol Gastrointest Liver Physiol. 2005 Sep;289(3):G530-8. doi: 10.1152/ajpgi.00526.2004. Epub 2005 May 19. Am J Physiol Gastrointest Liver Physiol. 2005. PMID: 15905413
Minimizing oxidative stress by gene delivery of superoxide dismutase accelerates regeneration after transplantation of reduced-size livers in the rat.
Lehmann TG, Luedde T, Schwabe RF, Bunzendahl H, Samulski RJ, Lemasters JJ, Brenner DA. Lehmann TG, et al. Among authors: brenner da. Liver Transpl. 2006 Apr;12(4):550-9. doi: 10.1002/lt.20632. Liver Transpl. 2006. PMID: 16555330
Liver regeneration is suppressed in small-for-size liver grafts after transplantation: involvement of c-Jun N-terminal kinase, cyclin D1, and defective energy supply.
Zhong Z, Schwabe RF, Kai Y, He L, Yang L, Bunzendahl H, Brenner DA, Lemasters JJ. Zhong Z, et al. Among authors: brenner da. Transplantation. 2006 Jul 27;82(2):241-50. doi: 10.1097/ Transplantation. 2006. PMID: 16858288
TNFalpha is required for cholestasis-induced liver fibrosis in the mouse.
Gäbele E, Froh M, Arteel GE, Uesugi T, Hellerbrand C, Schölmerich J, Brenner DA, Thurman RG, Rippe RA. Gäbele E, et al. Among authors: brenner da. Biochem Biophys Res Commun. 2009 Jan 16;378(3):348-53. doi: 10.1016/j.bbrc.2008.10.155. Epub 2008 Nov 6. Biochem Biophys Res Commun. 2009. PMID: 18996089 Free PMC article.
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