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A role for the unfolded protein response in optimizing antibody secretion.
Gunn KE, Gifford NM, Mori K, Brewer JW. Gunn KE, et al. Among authors: brewer jw. Mol Immunol. 2004 Jul;41(9):919-27. doi: 10.1016/j.molimm.2004.04.023. Mol Immunol. 2004. PMID: 15261464
Phosphatidylcholine as a metabolic cue for determining B cell fate and function.
Brewer JW, Solodushko V, Aragon I, Barrington RA. Brewer JW, et al. Cell Immunol. 2016 Dec;310:78-88. doi: 10.1016/j.cellimm.2016.08.002. Epub 2016 Aug 3. Cell Immunol. 2016. PMID: 27502364 Free PMC article.
UPR-Mediated Membrane Biogenesis in B Cells.
Brewer JW, Jackowski S. Brewer JW, et al. Biochem Res Int. 2012;2012:738471. doi: 10.1155/2012/738471. Epub 2011 Nov 1. Biochem Res Int. 2012. PMID: 22110962 Free PMC article.
Micro(RNA)managing endoplasmic reticulum stress.
Byrd AE, Brewer JW. Byrd AE, et al. Among authors: brewer jw. IUBMB Life. 2013 May;65(5):373-81. doi: 10.1002/iub.1151. Epub 2013 Apr 3. IUBMB Life. 2013. PMID: 23554021 Free PMC article. Review.
The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genes.
Bartoszewski R, Brewer JW, Rab A, Crossman DK, Bartoszewska S, Kapoor N, Fuller C, Collawn JF, Bebok Z. Bartoszewski R, et al. Among authors: brewer jw. J Biol Chem. 2011 Dec 2;286(48):41862-70. doi: 10.1074/jbc.M111.304956. Epub 2011 Oct 14. J Biol Chem. 2011. PMID: 22002058 Free PMC article.
Stable ribosome binding to the endoplasmic reticulum enables compartment-specific regulation of mRNA translation.
Stephens SB, Dodd RD, Brewer JW, Lager PJ, Keene JD, Nicchitta CV. Stephens SB, et al. Among authors: brewer jw. Mol Biol Cell. 2005 Dec;16(12):5819-31. doi: 10.1091/mbc.e05-07-0685. Epub 2005 Oct 12. Mol Biol Cell. 2005. PMID: 16221886 Free PMC article.
ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum.
Bommiasamy H, Back SH, Fagone P, Lee K, Meshinchi S, Vink E, Sriburi R, Frank M, Jackowski S, Kaufman RJ, Brewer JW. Bommiasamy H, et al. Among authors: brewer jw. J Cell Sci. 2009 May 15;122(Pt 10):1626-36. doi: 10.1242/jcs.045625. J Cell Sci. 2009. PMID: 19420237 Free PMC article.
Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis.
Sriburi R, Bommiasamy H, Buldak GL, Robbins GR, Frank M, Jackowski S, Brewer JW. Sriburi R, et al. Among authors: brewer jw. J Biol Chem. 2007 Mar 9;282(10):7024-34. doi: 10.1074/jbc.M609490200. Epub 2007 Jan 8. J Biol Chem. 2007. PMID: 17213183
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