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X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis.
Haslinger K, Peschke M, Brieke C, Maximowitsch E, Cryle MJ. Haslinger K, et al. Among authors: brieke c. Nature. 2015 May 7;521(7550):105-9. doi: 10.1038/nature14141. Epub 2015 Feb 9. Nature. 2015. PMID: 25686610
Structural aspects of phenylglycines, their biosynthesis and occurrence in peptide natural products.
Al Toma RS, Brieke C, Cryle MJ, Süssmuth RD. Al Toma RS, et al. Among authors: brieke c. Nat Prod Rep. 2015 Aug;32(8):1207-35. doi: 10.1039/c5np00025d. Nat Prod Rep. 2015. PMID: 25940955 Review.
F-O-G Ring Formation in Glycopeptide Antibiotic Biosynthesis is Catalysed by OxyE.
Peschke M, Brieke C, Cryle MJ. Peschke M, et al. Among authors: brieke c. Sci Rep. 2016 Oct 18;6:35584. doi: 10.1038/srep35584. Sci Rep. 2016. PMID: 27752135 Free PMC article.
The structure of a transient complex of a nonribosomal peptide synthetase and a cytochrome P450 monooxygenase.
Haslinger K, Brieke C, Uhlmann S, Sieverling L, Süssmuth RD, Cryle MJ. Haslinger K, et al. Among authors: brieke c. Angew Chem Int Ed Engl. 2014 Aug 4;53(32):8518-22. doi: 10.1002/anie.201404977. Epub 2014 Jul 9. Angew Chem Int Ed Engl. 2014. PMID: 25044735
3'-NADP and 3'-NAADP, Two Metabolites Formed by the Bacterial Type III Effector AvrRxo1.
Schuebel F, Rocker A, Edelmann D, Schessner J, Brieke C, Meinhart A. Schuebel F, et al. Among authors: brieke c. J Biol Chem. 2016 Oct 28;291(44):22868-22880. doi: 10.1074/jbc.M116.751297. Epub 2016 Sep 12. J Biol Chem. 2016. PMID: 27621317 Free PMC article.
Biochemical and structural characterisation of the second oxidative crosslinking step during the biosynthesis of the glycopeptide antibiotic A47934.
Ulrich V, Brieke C, Cryle MJ. Ulrich V, et al. Among authors: brieke c. Beilstein J Org Chem. 2016 Dec 27;12:2849-2864. doi: 10.3762/bjoc.12.284. eCollection 2016. Beilstein J Org Chem. 2016. PMID: 28144358 Free PMC article.
The ng_ζ1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis.
Rocker A, Peschke M, Kittilä T, Sakson R, Brieke C, Meinhart A. Rocker A, et al. Among authors: brieke c. Nat Commun. 2018 Apr 27;9(1):1686. doi: 10.1038/s41467-018-03652-8. Nat Commun. 2018. PMID: 29703974 Free PMC article.
Efficient cosubstrate enzyme pairs for sequence-specific methyltransferase-directed photolabile caging of DNA.
Heimes M , Kolmar L , Brieke C . Heimes M , et al. Among authors: brieke c. Chem Commun (Camb). 2018 Nov 8;54(90):12718-12721. doi: 10.1039/c8cc05913f. Chem Commun (Camb). 2018. PMID: 30357150
Investigating Cytochrome P450 specificity during glycopeptide antibiotic biosynthesis through a homologue hybridization approach.
Brieke C, Tarnawski M, Greule A, Cryle MJ. Brieke C, et al. J Inorg Biochem. 2018 Aug;185:43-51. doi: 10.1016/j.jinorgbio.2018.05.001. Epub 2018 May 3. J Inorg Biochem. 2018. PMID: 29751197
A route to diastereomerically pure phenylglycine thioester peptides: crucial intermediates for investigating glycopeptide antibiotic biosynthesis.
Tailhades J , Schoppet M , Greule A , Peschke M , Brieke C , Cryle MJ . Tailhades J , et al. Among authors: brieke c. Chem Commun (Camb). 2018 Feb 22;54(17):2146-2149. doi: 10.1039/c7cc09409d. Chem Commun (Camb). 2018. PMID: 29423498
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