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Neuromotor tolerability and behavioural characterisation of cannabidiolic acid, a phytocannabinoid with therapeutic potential for anticipatory nausea.
Brierley DI, Samuels J, Duncan M, Whalley BJ, Williams CM. Brierley DI, et al. Psychopharmacology (Berl). 2016 Jan;233(2):243-54. doi: 10.1007/s00213-015-4100-1. Epub 2015 Oct 6. Psychopharmacology (Berl). 2016. PMID: 26439367
Chemotherapy-induced cachexia dysregulates hypothalamic and systemic lipoamines and is attenuated by cannabigerol.
Brierley DI, Harman JR, Giallourou N, Leishman E, Roashan AE, Mellows BAD, Bradshaw HB, Swann JR, Patel K, Whalley BJ, Williams CM. Brierley DI, et al. J Cachexia Sarcopenia Muscle. 2019 Aug;10(4):844-859. doi: 10.1002/jcsm.12426. Epub 2019 Apr 29. J Cachexia Sarcopenia Muscle. 2019. PMID: 31035309 Free PMC article. Clinical Trial.
Cannabigerol is a novel, well-tolerated appetite stimulant in pre-satiated rats.
Brierley DI, Samuels J, Duncan M, Whalley BJ, Williams CM. Brierley DI, et al. Psychopharmacology (Berl). 2016 Oct;233(19-20):3603-13. doi: 10.1007/s00213-016-4397-4. Epub 2016 Aug 9. Psychopharmacology (Berl). 2016. PMID: 27503475 Free PMC article.
Harmine augments electrically evoked dopamine efflux in the nucleus accumbens shell.
Brierley DI, Davidson C. Brierley DI, et al. J Psychopharmacol. 2013 Jan;27(1):98-108. doi: 10.1177/0269881112463125. Epub 2012 Oct 17. J Psychopharmacol. 2013. PMID: 23076833
Developments in harmine pharmacology--implications for ayahuasca use and drug-dependence treatment.
Brierley DI, Davidson C. Brierley DI, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2012 Dec 3;39(2):263-72. doi: 10.1016/j.pnpbp.2012.06.001. Epub 2012 Jun 9. Prog Neuropsychopharmacol Biol Psychiatry. 2012. PMID: 22691716 Review.
Preproglucagon Neurons in the Nucleus of the Solitary Tract Are the Main Source of Brain GLP-1, Mediate Stress-Induced Hypophagia, and Limit Unusually Large Intakes of Food.
Holt MK, Richards JE, Cook DR, Brierley DI, Williams DL, Reimann F, Gribble FM, Trapp S. Holt MK, et al. Among authors: brierley di. Diabetes. 2019 Jan;68(1):21-33. doi: 10.2337/db18-0729. Epub 2018 Oct 2. Diabetes. 2019. PMID: 30279161 Free PMC article.
GLP-1 neurons form a local synaptic circuit within the rodent nucleus of the solitary tract.
Card JP, Johnson AL, Llewellyn-Smith IJ, Zheng H, Anand R, Brierley DI, Trapp S, Rinaman L. Card JP, et al. Among authors: brierley di. J Comp Neurol. 2018 Oct 1;526(14):2149-2164. doi: 10.1002/cne.24482. Epub 2018 Sep 19. J Comp Neurol. 2018. PMID: 30019398 Free PMC article.
Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli.
Brischoux F, Chakraborty S, Brierley DI, Ungless MA. Brischoux F, et al. Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4894-9. doi: 10.1073/pnas.0811507106. Epub 2009 Mar 4. Proc Natl Acad Sci U S A. 2009. PMID: 19261850 Free PMC article.
PPG neurons in the nucleus of the solitary tract modulate heart rate but do not mediate GLP-1 receptor agonist-induced tachycardia in mice.
Holt MK, Cook DR, Brierley DI, Richards JE, Reimann F, Gourine AV, Marina N, Trapp S. Holt MK, et al. Among authors: brierley di. Mol Metab. 2020 May 21;39:101024. doi: 10.1016/j.molmet.2020.101024. Online ahead of print. Mol Metab. 2020. PMID: 32446875 Free PMC article.
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