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Glutamate receptors regulate actin-based plasticity in dendritic spines.
Fischer M, Kaech S, Wagner U, Brinkhaus H, Matus A. Fischer M, et al. Among authors: brinkhaus h. Nat Neurosci. 2000 Sep;3(9):887-94. doi: 10.1038/78791. Nat Neurosci. 2000. PMID: 10966619
Influx of extracellular calcium regulates actin-dependent morphological plasticity in dendritic spines.
Brünig I, Kaech S, Brinkhaus H, Oertner TG, Matus A. Brünig I, et al. Among authors: brinkhaus h. Neuropharmacology. 2004 Oct;47(5):669-76. doi: 10.1016/j.neuropharm.2004.07.038. Neuropharmacology. 2004. PMID: 15458838
Interactions between drebrin and Ras regulate dendritic spine plasticity.
Biou V, Brinkhaus H, Malenka RC, Matus A. Biou V, et al. Among authors: brinkhaus h. Eur J Neurosci. 2008 Jun;27(11):2847-59. doi: 10.1111/j.1460-9568.2008.06269.x. Eur J Neurosci. 2008. PMID: 18588530
The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα.
Britschgi A, Duss S, Kim S, Couto JP, Brinkhaus H, Koren S, De Silva D, Mertz KD, Kaup D, Varga Z, Voshol H, Vissieres A, Leroy C, Roloff T, Stadler MB, Scheel CH, Miraglia LJ, Orth AP, Bonamy GM, Reddy VA, Bentires-Alj M. Britschgi A, et al. Among authors: brinkhaus h. Nature. 2017 Jan 26;541(7638):541-545. doi: 10.1038/nature20829. Epub 2017 Jan 9. Nature. 2017. PMID: 28068668 Free PMC article.
Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop.
Aceto N, Sausgruber N, Brinkhaus H, Gaidatzis D, Martiny-Baron G, Mazzarol G, Confalonieri S, Quarto M, Hu G, Balwierz PJ, Pachkov M, Elledge SJ, van Nimwegen E, Stadler MB, Bentires-Alj M. Aceto N, et al. Among authors: brinkhaus h. Nat Med. 2012 Mar 4;18(4):529-37. doi: 10.1038/nm.2645. Nat Med. 2012. PMID: 22388088
Actin dynamics in dendritic spines: a form of regulated plasticity at excitatory synapses.
Matus A, Brinkhaus H, Wagner U. Matus A, et al. Among authors: brinkhaus h. Hippocampus. 2000;10(5):555-60. doi: 10.1002/1098-1063(2000)10:5<555::AID-HIPO5>3.0.CO;2-Z. Hippocampus. 2000. PMID: 11075825 Review.
Volatile anesthetics block actin-based motility in dendritic spines.
Kaech S, Brinkhaus H, Matus A. Kaech S, et al. Among authors: brinkhaus h. Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10433-7. doi: 10.1073/pnas.96.18.10433. Proc Natl Acad Sci U S A. 1999. PMID: 10468626 Free PMC article.
Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling.
Britschgi A, Bill A, Brinkhaus H, Rothwell C, Clay I, Duss S, Rebhan M, Raman P, Guy CT, Wetzel K, George E, Popa MO, Lilley S, Choudhury H, Gosling M, Wang L, Fitzgerald S, Borawski J, Baffoe J, Labow M, Gaither LA, Bentires-Alj M. Britschgi A, et al. Among authors: brinkhaus h. Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):E1026-34. doi: 10.1073/pnas.1217072110. Epub 2013 Feb 19. Proc Natl Acad Sci U S A. 2013. PMID: 23431153 Free PMC article.
JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: a rationale for cotargeting these pathways in metastatic breast cancer.
Britschgi A, Andraos R, Brinkhaus H, Klebba I, Romanet V, Müller U, Murakami M, Radimerski T, Bentires-Alj M. Britschgi A, et al. Among authors: brinkhaus h. Cancer Cell. 2012 Dec 11;22(6):796-811. doi: 10.1016/j.ccr.2012.10.023. Cancer Cell. 2012. PMID: 23238015 Free article.
MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradation.
Shostak K, Patrascu F, Göktuna SI, Close P, Borgs L, Nguyen L, Olivier F, Rammal A, Brinkhaus H, Bentires-Alj M, Marine JC, Chariot A. Shostak K, et al. Among authors: brinkhaus h. Cell Death Differ. 2014 May;21(5):811-24. doi: 10.1038/cdd.2014.2. Epub 2014 Jan 31. Cell Death Differ. 2014. PMID: 24488098 Free PMC article.
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