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Role of CAS, a human homologue to the yeast chromosome segregation gene CSE1, in toxin and tumor necrosis factor mediated apoptosis.
Brinkmann U, Brinkmann E, Gallo M, Scherf U, Pastan I. Brinkmann U, et al. Among authors: brinkmann e. Biochemistry. 1996 May 28;35(21):6891-9. doi: 10.1021/bi952829+. Biochemistry. 1996. PMID: 8639641
We have previously isolated by expression/selection cloning plasmids containing human cDNAs that rendered MCF-7 breast cancer cells resistant to immunotoxins, Pseudomonas exotoxin (PE), and diphtheria toxin (DT) [Brinkmann et al. (1995) Mol. Med. 1, 206-216]. Here we descr …
We have previously isolated by expression/selection cloning plasmids containing human cDNAs that rendered MCF-7 breast cancer cells resistan …
CSE1L/CAS: its role in proliferation and apoptosis.
Behrens P, Brinkmann U, Wellmann A. Behrens P, et al. Among authors: brinkmann u. Apoptosis. 2003 Jan;8(1):39-44. doi: 10.1023/a:1021644918117. Apoptosis. 2003. PMID: 12510150 Review.
Loss of diphthamide pre-activates NF-κB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor.
Stahl S, da Silva Mateus Seidl AR, Ducret A, Kux van Geijtenbeek S, Michel S, Racek T, Birzele F, Haas AK, Rueger R, Gerg M, Niederfellner G, Pastan I, Brinkmann U. Stahl S, et al. Among authors: brinkmann u. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10732-7. doi: 10.1073/pnas.1512863112. Epub 2015 Aug 10. Proc Natl Acad Sci U S A. 2015. PMID: 26261303 Free PMC article.
Characterization of a re-engineered, mesothelin-targeted Pseudomonas exotoxin fusion protein for lung cancer therapy.
Bauss F, Lechmann M, Krippendorff BF, Staack R, Herting F, Festag M, Imhof-Jung S, Hesse F, Pompiati M, Kollmorgen G, da Silva Mateus Seidl R, Bossenmaier B, Lau W, Schantz C, Stracke JO, Brinkmann U, Onda M, Pastan I, Bosslet K, Niederfellner G. Bauss F, et al. Among authors: brinkmann u. Mol Oncol. 2016 Oct;10(8):1317-29. doi: 10.1016/j.molonc.2016.07.003. Epub 2016 Jul 14. Mol Oncol. 2016. PMID: 27507537 Free PMC article.
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