Brinkmann U - Search Results

1

Role of CAS, a human homologue to the yeast chromosome segregation gene CSE1, in toxin and tumor necrosis factor mediated apoptosis.

Brinkmann U, Brinkmann E, Gallo M, Scherf U, Pastan I. Brinkmann U, et al. Among authors: brinkmann e. Biochemistry. 1996 May 28;35(21):6891-9. doi: 10.1021/bi952829+. Biochemistry. 1996. PMID: 8639641

We have previously isolated by expression/selection cloning plasmids containing human cDNAs that rendered MCF-7 breast cancer cells resistant to immunotoxins, Pseudomonas exotoxin (PE), and diphtheria toxin (DT) [Brinkmann et al. (1995) Mol. Med. 1, 206-216]. Here we descr …

We have previously isolated by expression/selection cloning plasmids containing human cDNAs that rendered MCF-7 breast cancer cells resistan …

2

CSE1L/CAS: its role in proliferation and apoptosis.

Behrens P, Brinkmann U, Wellmann A. Behrens P, et al. Among authors: brinkmann u. Apoptosis. 2003 Jan;8(1):39-44. doi: 10.1023/a:1021644918117. Apoptosis. 2003. PMID: 12510150 Review.

3

Implication of the proliferation and apoptosis associated CSE1L/CAS gene for breast cancer development.

Behrens P, Brinkmann U, Fogt F, Wernert N, Wellmann A. Behrens P, et al. Among authors: brinkmann u. Anticancer Res. 2001 Jul-Aug;21(4A):2413-7. Anticancer Res. 2001. PMID: 11724300

4

Loss of diphthamide pre-activates NF-κB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor.

Stahl S, da Silva Mateus Seidl AR, Ducret A, Kux van Geijtenbeek S, Michel S, Racek T, Birzele F, Haas AK, Rueger R, Gerg M, Niederfellner G, Pastan I, Brinkmann U. Stahl S, et al. Among authors: brinkmann u. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10732-7. doi: 10.1073/pnas.1512863112. Epub 2015 Aug 10. Proc Natl Acad Sci U S A. 2015. PMID: 26261303 Free PMC article.

5

Characterization of a re-engineered, mesothelin-targeted Pseudomonas exotoxin fusion protein for lung cancer therapy.

Bauss F, Lechmann M, Krippendorff BF, Staack R, Herting F, Festag M, Imhof-Jung S, Hesse F, Pompiati M, Kollmorgen G, da Silva Mateus Seidl R, Bossenmaier B, Lau W, Schantz C, Stracke JO, Brinkmann U, Onda M, Pastan I, Bosslet K, Niederfellner G. Bauss F, et al. Among authors: brinkmann u. Mol Oncol. 2016 Oct;10(8):1317-29. doi: 10.1016/j.molonc.2016.07.003. Epub 2016 Jul 14. Mol Oncol. 2016. PMID: 27507537 Free PMC article.

6

Attenuating the growth of tumors by intratumoral administration of DNA encoding Pseudomonas exotoxin via cationic liposomes.

Yerushalmi N, Brinkmann U, Brinkmann E, Pai L, Pastan I. Yerushalmi N, et al. Among authors: brinkmann u, brinkmann e. Cancer Gene Ther. 2000 Jan;7(1):91-6. doi: 10.1038/sj.cgt.7700115. Cancer Gene Ther. 2000. PMID: 10678361

7

CAS, the human homologue of the yeast chromosome-segregation gene CSE1, in proliferation, apoptosis, and cancer.

Brinkmann U. Brinkmann U. Am J Hum Genet. 1998 Mar;62(3):509-13. doi: 10.1086/301773. Am J Hum Genet. 1998. PMID: 9497270 Free PMC article. Review. No abstract available.

8

The human CAS (cellular apoptosis susceptibility) gene mapping on chromosome 20q13 is amplified in BT474 breast cancer cells and part of aberrant chromosomes in breast and colon cancer cell lines.

Brinkmann U, Gallo M, Polymeropoulos MH, Pastan I. Brinkmann U, et al. Genome Res. 1996 Mar;6(3):187-94. doi: 10.1101/gr.6.3.187. Genome Res. 1996. PMID: 8963895

9

Adenovirus-mediated gene transfer to human breast tumor cells: an approach for cancer gene therapy and bone marrow purging.

Seth P, Brinkmann U, Schwartz GN, Katayose D, Gress R, Pastan Ira, Cowan K. Seth P, et al. Among authors: brinkmann u. Cancer Res. 1996 Mar 15;56(6):1346-51. Cancer Res. 1996. PMID: 8640824

10

The human CAS protein which is homologous to the CSE1 yeast chromosome segregation gene product is associated with microtubules and mitotic spindle.

Scherf U, Pastan I, Willingham MC, Brinkmann U. Scherf U, et al. Among authors: brinkmann u. Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2670-4. doi: 10.1073/pnas.93.7.2670. Proc Natl Acad Sci U S A. 1996. PMID: 8610099 Free PMC article.

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