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Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner.
Hirao A, Cheung A, Duncan G, Girard PM, Elia AJ, Wakeham A, Okada H, Sarkissian T, Wong JA, Sakai T, De Stanchina E, Bristow RG, Suda T, Lowe SW, Jeggo PA, Elledge SJ, Mak TW. Hirao A, et al. Among authors: bristow rg. Mol Cell Biol. 2002 Sep;22(18):6521-32. doi: 10.1128/mcb.22.18.6521-6532.2002. Mol Cell Biol. 2002. PMID: 12192050 Free PMC article.
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