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The ageing systemic milieu negatively regulates neurogenesis and cognitive function.
Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Després S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T. Villeda SA, et al. Among authors: britschgi m. Nature. 2011 Aug 31;477(7362):90-4. doi: 10.1038/nature10357. Nature. 2011. PMID: 21886162 Free PMC article.
Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease.
Britschgi M, Olin CE, Johns HT, Takeda-Uchimura Y, LeMieux MC, Rufibach K, Rajadas J, Zhang H, Tomooka B, Robinson WH, Clark CM, Fagan AM, Galasko DR, Holtzman DM, Jutel M, Kaye JA, Lemere CA, Leszek J, Li G, Peskind ER, Quinn JF, Yesavage JA, Ghiso JA, Wyss-Coray T. Britschgi M, et al. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12145-50. doi: 10.1073/pnas.0904866106. Epub 2009 Jul 6. Proc Natl Acad Sci U S A. 2009. PMID: 19581601 Free PMC article.
Immune cells may fend off Alzheimer disease.
Britschgi M, Wyss-Coray T. Britschgi M, et al. Nat Med. 2007 Apr;13(4):408-9. doi: 10.1038/nm0407-408. Nat Med. 2007. PMID: 17415372 No abstract available.
Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins.
Ray S, Britschgi M, Herbert C, Takeda-Uchimura Y, Boxer A, Blennow K, Friedman LF, Galasko DR, Jutel M, Karydas A, Kaye JA, Leszek J, Miller BL, Minthon L, Quinn JF, Rabinovici GD, Robinson WH, Sabbagh MN, So YT, Sparks DL, Tabaton M, Tinklenberg J, Yesavage JA, Tibshirani R, Wyss-Coray T. Ray S, et al. Among authors: britschgi m. Nat Med. 2007 Nov;13(11):1359-62. doi: 10.1038/nm1653. Epub 2007 Oct 14. Nat Med. 2007. PMID: 17934472
Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival.
Luo J, Elwood F, Britschgi M, Villeda S, Zhang H, Ding Z, Zhu L, Alabsi H, Getachew R, Narasimhan R, Wabl R, Fainberg N, James ML, Wong G, Relton J, Gambhir SS, Pollard JW, Wyss-Coray T. Luo J, et al. Among authors: britschgi m. J Exp Med. 2013 Jan 14;210(1):157-72. doi: 10.1084/jem.20120412. Epub 2013 Jan 7. J Exp Med. 2013. PMID: 23296467 Free PMC article.
Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity.
Czirr E, Castello NA, Mosher KI, Castellano JM, Hinkson IV, Lucin KM, Baeza-Raja B, Ryu JK, Li L, Farina SN, Belichenko NP, Longo FM, Akassoglou K, Britschgi M, Cirrito JR, Wyss-Coray T. Czirr E, et al. Among authors: britschgi m. J Exp Med. 2017 Apr 3;214(4):1081-1092. doi: 10.1084/jem.20162011. Epub 2017 Mar 15. J Exp Med. 2017. PMID: 28298456 Free PMC article.
68 results