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26 results
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Challenges for gene therapy of CNS disorders and implications for Parkinson's disease therapies.
Broadstock M, Yáñez-Muñoz RJ. Broadstock M, et al. Hum Gene Ther. 2012 Apr;23(4):340-3. doi: 10.1089/hum.2012.2507. Epub 2012 Apr 10. Hum Gene Ther. 2012. PMID: 22490128 No abstract available.
Antiparkinsonian potential of targeting group III metabotropic glutamate receptor subtypes in the rodent substantia nigra pars reticulata.
Broadstock M, Austin PJ, Betts MJ, Duty S. Broadstock M, et al. Br J Pharmacol. 2012 Feb;165(4b):1034-45. doi: 10.1111/j.1476-5381.2011.01515.x. Br J Pharmacol. 2012. PMID: 21627638 Free PMC article.
Synaptic protein expression is regulated by a pro-oxidant diet in APPxPS1 mice.
Broadstock M, Lewinsky R, Jones EL, Mitchelmore C, Howlett DR, Francis PT. Broadstock M, et al. J Neural Transm (Vienna). 2012 Apr;119(4):493-6. doi: 10.1007/s00702-011-0727-1. Epub 2011 Nov 5. J Neural Transm (Vienna). 2012. PMID: 22057511
Transgenic expression of human glial cell line-derived neurotrophic factor from integration-deficient lentiviral vectors is neuroprotective in a rodent model of Parkinson's disease.
Lu-Nguyen NB, Broadstock M, Schliesser MG, Bartholomae CC, von Kalle C, Schmidt M, Yáñez-Muñoz RJ. Lu-Nguyen NB, et al. Among authors: broadstock m. Hum Gene Ther. 2014 Jul;25(7):631-41. doi: 10.1089/hum.2014.003. Epub 2014 Apr 15. Hum Gene Ther. 2014. PMID: 24635742 Free PMC article.
Latest treatment options for Alzheimer's disease, Parkinson's disease dementia and dementia with Lewy bodies.
Broadstock M, Ballard C, Corbett A. Broadstock M, et al. Expert Opin Pharmacother. 2014 Sep;15(13):1797-810. doi: 10.1517/14656566.2014.936848. Epub 2014 Jul 3. Expert Opin Pharmacother. 2014. PMID: 24992196 Review.
Novel pharmaceuticals in the treatment of psychosis in Parkinson's disease.
Broadstock M, Ballard C, Corbett A. Broadstock M, et al. Expert Rev Clin Pharmacol. 2014 Nov;7(6):779-86. doi: 10.1586/17512433.2014.966814. Epub 2014 Oct 10. Expert Rev Clin Pharmacol. 2014. PMID: 25301532 Review.
Efficient Expression of Igf-1 from Lentiviral Vectors Protects In Vitro but Does Not Mediate Behavioral Recovery of a Parkinsonian Lesion in Rats.
Lu-Nguyen NB, Broadstock M, Yáñez-Muñoz RJ. Lu-Nguyen NB, et al. Among authors: broadstock m. Hum Gene Ther. 2015 Nov;26(11):719-33. doi: 10.1089/hum.2015.016. Epub 2015 Oct 1. Hum Gene Ther. 2015. PMID: 26222254 Free PMC article.
A genetically immortalized human stem cell line: a promising new tool for Alzheimer's disease therapy.
Puangmalai N, Somani A, Thangnipon W, Ballard C, Broadstock M. Puangmalai N, et al. Among authors: broadstock m. EXCLI J. 2015 Oct 21;14:1135-14. doi: 10.17179/excli2015-560. eCollection 2015. EXCLI J. 2015. PMID: 27152108 Free PMC article.
Intrastriatal Delivery of Integration-Deficient Lentiviral Vectors in a Rat Model of Parkinson's Disease.
Lu-Nguyen NB, Broadstock M, Yáñez-Muñoz RJ. Lu-Nguyen NB, et al. Among authors: broadstock m. Methods Mol Biol. 2016;1448:175-84. doi: 10.1007/978-1-4939-3753-0_13. Methods Mol Biol. 2016. PMID: 27317181
Neurochemical changes in a double transgenic mouse model of Alzheimer's disease fed a pro-oxidant diet.
Ash ES, Alavijeh MS, Palmer AM, Mitchelmore C, Howlett DR, Francis PT, Broadstock M, Richardson JC. Ash ES, et al. Among authors: broadstock m. Neurochem Int. 2010 Nov;57(5):504-11. doi: 10.1016/j.neuint.2010.06.013. Epub 2010 Jun 30. Neurochem Int. 2010. PMID: 20600435
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