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NAT2*12A (803A-->G) codes for rapid arylamine n-acetylation in humans.
Cascorbi I, Brockmöller J, Bauer S, Reum T, Roots I. Cascorbi I, et al. Among authors: brockmoller j. Pharmacogenetics. 1996 Jun;6(3):257-9. doi: 10.1097/00008571-199606000-00009. Pharmacogenetics. 1996. PMID: 8807666 No abstract available.
Characterization of the glutathione S-transferase GSTT1 deletion: discrimination of all genotypes by polymerase chain reaction indicates a trimodular genotype-phenotype correlation.
Sprenger R, Schlagenhaufer R, Kerb R, Bruhn C, Brockmöller J, Roots I, Brinkmann U. Sprenger R, et al. Among authors: brockmoller j. Pharmacogenetics. 2000 Aug;10(6):557-65. doi: 10.1097/00008571-200008000-00009. Pharmacogenetics. 2000. PMID: 10975610
Mutant genes of cytochrome P-450IID6, glutathione S-transferase class Mu, and arylamine N-acetyltransferase in lung cancer patients.
Roots I, Brockmöller J, Drakoulis N, Loddenkemper R. Roots I, et al. Among authors: brockmoller j. Clin Investig. 1992 Mar-Apr;70(3-4):307-19. doi: 10.1007/BF00184667. Clin Investig. 1992. PMID: 1355678
The genetic determinants of the CYP3A5 polymorphism.
Hustert E, Haberl M, Burk O, Wolbold R, He YQ, Klein K, Nuessler AC, Neuhaus P, Klattig J, Eiselt R, Koch I, Zibat A, Brockmöller J, Halpert JR, Zanger UM, Wojnowski L. Hustert E, et al. Among authors: brockmoller j. Pharmacogenetics. 2001 Dec;11(9):773-9. doi: 10.1097/00008571-200112000-00005. Pharmacogenetics. 2001. PMID: 11740341
Identification and functional characterization of eight CYP3A4 protein variants.
Eiselt R, Domanski TL, Zibat A, Mueller R, Presecan-Siedel E, Hustert E, Zanger UM, Brockmoller J, Klenk HP, Meyer UA, Khan KK, He YA, Halpert JR, Wojnowski L. Eiselt R, et al. Among authors: brockmoller j. Pharmacogenetics. 2001 Jul;11(5):447-58. doi: 10.1097/00008571-200107000-00008. Pharmacogenetics. 2001. PMID: 11470997
Correctness of prediction of the CYP2D6 phenotype confirmed by genotyping 47 intermediate and poor metabolizers of debrisoquine.
Sachse C, Brockmöller J, Hildebrand M, Müller K, Roots I. Sachse C, et al. Among authors: brockmoller j. Pharmacogenetics. 1998 Apr;8(2):181-5. Pharmacogenetics. 1998. PMID: 10022755 No abstract available.
High benzo[a]pyrene diol-epoxide DNA adduct levels in lung and blood cells from individuals with combined CYP1A1 MspI/Msp-GSTM1*0/*0 genotypes.
Rojas M, Alexandrov K, Cascorbi I, Brockmöller J, Likhachev A, Pozharisski K, Bouvier G, Auburtin G, Mayer L, Kopp-Schneider A, Roots I, Bartsch H. Rojas M, et al. Among authors: brockmoller j. Pharmacogenetics. 1998 Apr;8(2):109-18. Pharmacogenetics. 1998. PMID: 10022748
A rare insertion of T226 in exon 1 of CYP2D6 causes a frameshift and is associated with the poor metabolizer phenotype: CYP2D6*15.
Sachse C, Brockmöller J, Bauer S, Reum T, Roots I. Sachse C, et al. Among authors: brockmoller j. Pharmacogenetics. 1996 Jun;6(3):269-72. doi: 10.1097/00008571-199606000-00012. Pharmacogenetics. 1996. PMID: 8807669 No abstract available.
Nomenclature for human CYP2D6 alleles.
Daly AK, Brockmöller J, Broly F, Eichelbaum M, Evans WE, Gonzalez FJ, Huang JD, Idle JR, Ingelman-Sundberg M, Ishizaki T, Jacqz-Aigrain E, Meyer UA, Nebert DW, Steen VM, Wolf CR, Zanger UM. Daly AK, et al. Among authors: brockmoller j. Pharmacogenetics. 1996 Jun;6(3):193-201. doi: 10.1097/00008571-199606000-00001. Pharmacogenetics. 1996. PMID: 8807658
Simultaneous assessment of CYP3A4 and CYP1A2 activity in vivo with alprazolam and caffeine.
Schmider J, Brockmöller J, Arold G, Bauer S, Roots I. Schmider J, et al. Among authors: brockmoller j. Pharmacogenetics. 1999 Dec;9(6):725-34. doi: 10.1097/01213011-199912000-00007. Pharmacogenetics. 1999. PMID: 10634135 Clinical Trial.
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