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Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients.
Lee PP, Yee C, Savage PA, Fong L, Brockstedt D, Weber JS, Johnson D, Swetter S, Thompson J, Greenberg PD, Roederer M, Davis MM. Lee PP, et al. Among authors: brockstedt d. Nat Med. 1999 Jun;5(6):677-85. doi: 10.1038/9525. Nat Med. 1999. PMID: 10371507
Radiation therapy combined with Listeria monocytogenes-based cancer vaccine synergize to enhance tumor control in the B16 melanoma model.
Lim JY, Brockstedt DG, Lord EM, Gerber SA. Lim JY, et al. Oncoimmunology. 2014 Jun 3;3:e29028. doi: 10.4161/onci.29028. eCollection 2014. Oncoimmunology. 2014. PMID: 25083327 Free PMC article.
Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity.
Chan CW, Crafton E, Fan HN, Flook J, Yoshimura K, Skarica M, Brockstedt D, Dubensky TW, Stins MF, Lanier LL, Pardoll DM, Housseau F. Chan CW, et al. Among authors: brockstedt d. Nat Med. 2006 Feb;12(2):207-13. doi: 10.1038/nm1352. Epub 2006 Jan 29. Nat Med. 2006. PMID: 16444266
Induction of immunity to antigens expressed by recombinant adeno-associated virus depends on the route of administration.
Brockstedt DG, Podsakoff GM, Fong L, Kurtzman G, Mueller-Ruchholtz W, Engleman EG. Brockstedt DG, et al. Clin Immunol. 1999 Jul;92(1):67-75. doi: 10.1006/clim.1999.4724. Clin Immunol. 1999. PMID: 10413654
Killed but metabolically active microbes: a new vaccine paradigm for eliciting effector T-cell responses and protective immunity.
Brockstedt DG, Bahjat KS, Giedlin MA, Liu W, Leong M, Luckett W, Gao Y, Schnupf P, Kapadia D, Castro G, Lim JY, Sampson-Johannes A, Herskovits AA, Stassinopoulos A, Bouwer HG, Hearst JE, Portnoy DA, Cook DN, Dubensky TW Jr. Brockstedt DG, et al. Nat Med. 2005 Aug;11(8):853-60. doi: 10.1038/nm1276. Epub 2005 Jul 24. Nat Med. 2005. PMID: 16041382
Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis.
Schietinger A, Philip M, Krisnawan VE, Chiu EY, Delrow JJ, Basom RS, Lauer P, Brockstedt DG, Knoblaugh SE, Hämmerling GJ, Schell TD, Garbi N, Greenberg PD. Schietinger A, et al. Among authors: brockstedt dg. Immunity. 2016 Aug 16;45(2):389-401. doi: 10.1016/j.immuni.2016.07.011. Epub 2016 Aug 9. Immunity. 2016. PMID: 27521269 Free PMC article.
Listeria monocytogenes as a vaccine vector: virulence attenuation or existing antivector immunity does not diminish therapeutic efficacy.
Starks H, Bruhn KW, Shen H, Barry RA, Dubensky TW, Brockstedt D, Hinrichs DJ, Higgins DE, Miller JF, Giedlin M, Bouwer HG. Starks H, et al. Among authors: brockstedt d. J Immunol. 2004 Jul 1;173(1):420-7. doi: 10.4049/jimmunol.173.1.420. J Immunol. 2004. PMID: 15210801
Introduction of soluble proteins into the MHC class I pathway by conjugation to an HIV tat peptide.
Kim DT, Mitchell DJ, Brockstedt DG, Fong L, Nolan GP, Fathman CG, Engleman EG, Rothbard JB. Kim DT, et al. Among authors: brockstedt dg. J Immunol. 1997 Aug 15;159(4):1666-8. J Immunol. 1997. PMID: 9257826
Enhanced virus-specific CD8+ T cell responses by Listeria monocytogenes-infected dendritic cells in the context of Tim-3 blockade.
Ma CJ, Ren JP, Li GY, Wu XY, Brockstedt DG, Lauer P, Moorman JP, Yao ZQ. Ma CJ, et al. PLoS One. 2014 Jan 31;9(1):e87821. doi: 10.1371/journal.pone.0087821. eCollection 2014. PLoS One. 2014. PMID: 24498204 Free PMC article. Clinical Trial.
Listeria-based cancer vaccines that segregate immunogenicity from toxicity.
Brockstedt DG, Giedlin MA, Leong ML, Bahjat KS, Gao Y, Luckett W, Liu W, Cook DN, Portnoy DA, Dubensky TW Jr. Brockstedt DG, et al. Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13832-7. doi: 10.1073/pnas.0406035101. Epub 2004 Sep 13. Proc Natl Acad Sci U S A. 2004. PMID: 15365184 Free PMC article.
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