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l- to d-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics.
Ballabio F, Broggini L, Paissoni C, Han X, Peqini K, Sala BM, Sun R, Sandalova T, Barbiroli A, Achour A, Pellegrino S, Ricagno S, Camilloni C. Ballabio F, et al. Among authors: broggini l. ACS Omega. 2022 Mar 7;7(11):9622-9635. doi: 10.1021/acsomega.1c06964. eCollection 2022 Mar 22. ACS Omega. 2022. PMID: 35350306 Free PMC article.
Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity.
Achour A, Broggini L, Han X, Sun R, Santambrogio C, Buratto J, Visentin C, Barbiroli A, De Luca CMG, Sormanni P, Moda F, De Simone A, Sandalova T, Grandori R, Camilloni C, Ricagno S. Achour A, et al. Among authors: broggini l. FEBS J. 2020 Feb;287(3):546-560. doi: 10.1111/febs.15046. Epub 2019 Aug 28. FEBS J. 2020. PMID: 31420997 Free article.
Glycosylation Tunes Neuroserpin Physiological and Pathological Properties.
Visentin C, Broggini L, Sala BM, Russo R, Barbiroli A, Santambrogio C, Nonnis S, Dubnovitsky A, Bolognesi M, Miranda E, Achour A, Ricagno S. Visentin C, et al. Among authors: broggini l. Int J Mol Sci. 2020 May 3;21(9):3235. doi: 10.3390/ijms21093235. Int J Mol Sci. 2020. PMID: 32375228 Free PMC article.
Multi-eGO: An in silico lens to look into protein aggregation kinetics at atomic resolution.
Scalone E, Broggini L, Visentin C, Erba D, Bačić Toplek F, Peqini K, Pellegrino S, Ricagno S, Paissoni C, Camilloni C. Scalone E, et al. Among authors: broggini l. Proc Natl Acad Sci U S A. 2022 Jun 28;119(26):e2203181119. doi: 10.1073/pnas.2203181119. Epub 2022 Jun 23. Proc Natl Acad Sci U S A. 2022. PMID: 35737839 Free PMC article.
Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors.
Visentin C, Musso L, Broggini L, Bonato F, Russo R, Moriconi C, Bolognesi M, Miranda E, Dallavalle S, Passarella D, Ricagno S. Visentin C, et al. Among authors: broggini l. Life (Basel). 2020 Jul 11;10(7):111. doi: 10.3390/life10070111. Life (Basel). 2020. PMID: 32664592 Free PMC article.
β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression.
Hofbauer D, Mougiakakos D, Broggini L, Zaiss M, Büttner-Herold M, Bach C, Spriewald B, Neumann F, Bisht S, Nolting J, Zeiser R, Hamarsheh S, Eberhardt M, Vera J, Visentin C, De Luca CMG, Moda F, Haskamp S, Flamann C, Böttcher M, Bitterer K, Völkl S, Mackensen A, Ricagno S, Bruns H. Hofbauer D, et al. Among authors: broggini l. Immunity. 2021 Aug 10;54(8):1772-1787.e9. doi: 10.1016/j.immuni.2021.07.002. Epub 2021 Jul 20. Immunity. 2021. PMID: 34289378 Free article.
Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation.
Broggini L, Barzago MM, Speranzini V, Schulte T, Sonzini F, Giono M, Romeo M, Milani P, Caminito S, Mazzini G, Rognoni P, Merlini G, Pappone C, Anastasia L, Nuvolone M, Palladini G, Diomede L, Ricagno S. Broggini L, et al. J Mol Biol. 2023 Dec 15;435(24):168320. doi: 10.1016/j.jmb.2023.168320. Epub 2023 Oct 20. J Mol Biol. 2023. PMID: 37865287