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Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel.
Brohawn SG, Campbell EB, MacKinnon R. Brohawn SG, et al. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2129-34. doi: 10.1073/pnas.1218950110. Epub 2013 Jan 22. Proc Natl Acad Sci U S A. 2013. PMID: 23341632 Free PMC article.
Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+ channels.
Brohawn SG, Su Z, MacKinnon R. Brohawn SG, et al. Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3614-9. doi: 10.1073/pnas.1320768111. Epub 2014 Feb 18. Proc Natl Acad Sci U S A. 2014. PMID: 24550493 Free PMC article.
Studying Mechanosensitivity of Two-Pore Domain K+ Channels in Cellular and Reconstituted Proteoliposome Membranes.
Del Mármol J, Rietmeijer RA, Brohawn SG. Del Mármol J, et al. Among authors: brohawn sg. Methods Mol Biol. 2018;1684:129-150. doi: 10.1007/978-1-4939-7362-0_11. Methods Mol Biol. 2018. PMID: 29058189 Free PMC article.
The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier.
Brohawn SG, Wang W, Handler A, Campbell EB, Schwarz JR, MacKinnon R. Brohawn SG, et al. Elife. 2019 Nov 1;8:e50403. doi: 10.7554/eLife.50403. Elife. 2019. PMID: 31674909 Free PMC article.
Structural evidence for common ancestry of the nuclear pore complex and vesicle coats.
Brohawn SG, Leksa NC, Spear ED, Rajashankar KR, Schwartz TU. Brohawn SG, et al. Science. 2008 Nov 28;322(5906):1369-73. doi: 10.1126/science.1165886. Epub 2008 Oct 30. Science. 2008. PMID: 18974315 Free PMC article.
Precise multimodal optical control of neural ensemble activity.
Mardinly AR, Oldenburg IA, Pégard NC, Sridharan S, Lyall EH, Chesnov K, Brohawn SG, Waller L, Adesnik H. Mardinly AR, et al. Among authors: brohawn sg. Nat Neurosci. 2018 Jun;21(6):881-893. doi: 10.1038/s41593-018-0139-8. Epub 2018 Apr 30. Nat Neurosci. 2018. PMID: 29713079 Free PMC article.
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