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Page 1
The specificity and topology of chromatin interaction pathways in yeast.
Lenstra TL, Benschop JJ, Kim T, Schulze JM, Brabers NA, Margaritis T, van de Pasch LA, van Heesch SA, Brok MO, Groot Koerkamp MJ, Ko CW, van Leenen D, Sameith K, van Hooff SR, Lijnzaad P, Kemmeren P, Hentrich T, Kobor MS, Buratowski S, Holstege FC. Lenstra TL, et al. Among authors: brok mo. Mol Cell. 2011 May 20;42(4):536-49. doi: 10.1016/j.molcel.2011.03.026. Mol Cell. 2011. PMID: 21596317 Free PMC article.
Functional overlap and regulatory links shape genetic interactions between signaling pathways.
van Wageningen S, Kemmeren P, Lijnzaad P, Margaritis T, Benschop JJ, de Castro IJ, van Leenen D, Groot Koerkamp MJ, Ko CW, Miles AJ, Brabers N, Brok MO, Lenstra TL, Fiedler D, Fokkens L, Aldecoa R, Apweiler E, Taliadouros V, Sameith K, van de Pasch LA, van Hooff SR, Bakker LV, Krogan NJ, Snel B, Holstege FC. van Wageningen S, et al. Among authors: brok mo. Cell. 2010 Dec 10;143(6):991-1004. doi: 10.1016/j.cell.2010.11.021. Cell. 2010. PMID: 21145464 Free PMC article.
Exploring gene expression signatures for predicting disease free survival after resection of colorectal cancer liver metastases.
Snoeren N, van Hooff SR, Adam R, van Hillegersberg R, Voest EE, Guettier C, van Diest PJ, Nijkamp MW, Brok MO, van Leenen D, Koerkamp MJ, Holstege FC, Rinkes IH. Snoeren N, et al. Among authors: brok mo. PLoS One. 2012;7(11):e49442. doi: 10.1371/journal.pone.0049442. Epub 2012 Nov 21. PLoS One. 2012. PMID: 23185333 Free PMC article.
Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.
Kemmeren P, Sameith K, van de Pasch LA, Benschop JJ, Lenstra TL, Margaritis T, O'Duibhir E, Apweiler E, van Wageningen S, Ko CW, van Heesch S, Kashani MM, Ampatziadis-Michailidis G, Brok MO, Brabers NA, Miles AJ, Bouwmeester D, van Hooff SR, van Bakel H, Sluiters E, Bakker LV, Snel B, Lijnzaad P, van Leenen D, Groot Koerkamp MJ, Holstege FC. Kemmeren P, et al. Among authors: brok mo. Cell. 2014 Apr 24;157(3):740-52. doi: 10.1016/j.cell.2014.02.054. Cell. 2014. PMID: 24766815 Free article.
Cell cycle population effects in perturbation studies.
O'Duibhir E, Lijnzaad P, Benschop JJ, Lenstra TL, van Leenen D, Groot Koerkamp MJ, Margaritis T, Brok MO, Kemmeren P, Holstege FC. O'Duibhir E, et al. Among authors: brok mo. Mol Syst Biol. 2014 Jun 21;10(6):732. doi: 10.15252/msb.20145172. Mol Syst Biol. 2014. PMID: 24952590 Free PMC article.
A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions.
Sameith K, Amini S, Groot Koerkamp MJ, van Leenen D, Brok M, Brabers N, Lijnzaad P, van Hooff SR, Benschop JJ, Lenstra TL, Apweiler E, van Wageningen S, Snel B, Holstege FC, Kemmeren P. Sameith K, et al. BMC Biol. 2015 Dec 23;13:112. doi: 10.1186/s12915-015-0222-5. BMC Biol. 2015. PMID: 26700642 Free PMC article.
Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes.
Meister MT, Groot Koerkamp MJA, de Souza T, Breunis WB, Frazer-Mendelewska E, Brok M, DeMartino J, Manders F, Calandrini C, Kerstens HHD, Janse A, Dolman MEM, Eising S, Langenberg KPS, van Tuil M, Knops RRG, van Scheltinga ST, Hiemcke-Jiwa LS, Flucke U, Merks JHM, van Noesel MM, Tops BBJ, Hehir-Kwa JY, Kemmeren P, Molenaar JJ, van de Wetering M, van Boxtel R, Drost J, Holstege FCP. Meister MT, et al. EMBO Mol Med. 2022 Oct 10;14(10):e16001. doi: 10.15252/emmm.202216001. Epub 2022 Aug 2. EMBO Mol Med. 2022. PMID: 35916583 Free PMC article.
16 results