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Differential insertion of GPI-anchored GFPs into lipid rafts of live cells.
Legler DF, Doucey MA, Schneider P, Chapatte L, Bender FC, Bron C. Legler DF, et al. FASEB J. 2005 Jan;19(1):73-5. doi: 10.1096/fj.03-1338fje. Epub 2004 Oct 29. FASEB J. 2005. PMID: 15516372
CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation.
Gaide O, Favier B, Legler DF, Bonnet D, Brissoni B, Valitutti S, Bron C, Tschopp J, Thome M. Gaide O, et al. Nat Immunol. 2002 Sep;3(9):836-43. doi: 10.1038/ni830. Epub 2002 Aug 5. Nat Immunol. 2002. PMID: 12154360
A CARMA1 mutant, defective for Bcl10 binding, had a dominant-negative (DN) effect on TCR-induced NF-kappa B activation and IL-2 production and on the c-Jun NH(2)-terminal kinase (Jnk) pathway when the TCR was coengaged with CD28. ...
A CARMA1 mutant, defective for Bcl10 binding, had a dominant-negative (DN) effect on TCR-induced NF-kappa B activation and IL-2 production a …
The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation.
Doucey MA, Legler DF, Faroudi M, Boucheron N, Baumgaertner P, Naeher D, Cebecauer M, Hudrisier D, Rüegg C, Palmer E, Valitutti S, Bron C, Luescher IF. Doucey MA, et al. J Biol Chem. 2003 Jul 18;278(29):26983-91. doi: 10.1074/jbc.M302709200. Epub 2003 Apr 10. J Biol Chem. 2003. PMID: 12690105
CTL activation is induced by cross-linking of TCR/MHC-peptide-CD8/p56lck adducts in rafts.
Doucey MA, Legler DF, Boucheron N, Cerottini JC, Bron C, Luescher IF. Doucey MA, et al. Eur J Immunol. 2001 May;31(5):1561-70. doi: 10.1002/1521-4141(200105)31:5<1561::AID-IMMU1561>3.0.CO;2-W. Eur J Immunol. 2001. PMID: 11465114
Characterization of the non-functional Fas ligand of gld mice.
Hahne M, Peitsch MC, Irmler M, Schröter M, Lowin B, Rousseau M, Bron C, Renno T, French L, Tschopp J. Hahne M, et al. Int Immunol. 1995 Sep;7(9):1381-6. doi: 10.1093/intimm/7.9.1381. Int Immunol. 1995. PMID: 7495745
The lpr mutation is characterized by the absence of functional Fas, whereas gld mice exhibit an inactive FasL due to a point mutation proximal to the extracellular C-terminus. ...
The lpr mutation is characterized by the absence of functional Fas, whereas gld mice exhibit an inactive FasL due to a point mutation proxim …
Association of the Epstein-Barr virus latent membrane protein 1 with lipid rafts is mediated through its N-terminal region.
Rothenberger S, Rousseaux M, Knecht H, Bender FC, Legler DF, Bron C. Rothenberger S, et al. Cell Mol Life Sci. 2002 Jan;59(1):171-80. doi: 10.1007/s00018-002-8413-y. Cell Mol Life Sci. 2002. PMID: 11846027
An LMP1 mutant lacking the C-terminal 55 amino acids (Cdelta55) behaves like the wild-type (WT) LMP1 with respect to membrane localization. ...
An LMP1 mutant lacking the C-terminal 55 amino acids (Cdelta55) behaves like the wild-type (WT) LMP1 with respect to membrane localiz …
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