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222 results

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A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance.
Mertens RT, Misra A, Xiao P, Baek S, Rone JM, Mangani D, Sivanathan KN, Arojojoye AS, Awuah SG, Lee I, Shi GP, Petrova B, Brook JR, Anderson AC, Flavell RA, Kanarek N, Hemberg M, Nowarski R. Mertens RT, et al. Among authors: brook jr. Immunity. 2024 Sep 10;57(9):2077-2094.e12. doi: 10.1016/j.immuni.2024.06.001. Epub 2024 Jun 20. Immunity. 2024. PMID: 38906145 Free article.
Branched-chain ketoacid antioxidants mediate disease tolerance to sepsis.
Misra A, Weitman EM, Weitman M, Brook JR, Rone JM, Petrova B, Mertens RT, Hwang N, Vera KZ, Perrella MA, Baron RM, Kanarek N, Nowarski R. Misra A, et al. Among authors: brook jr. bioRxiv [Preprint]. 2025 May 22:2025.05.22.654748. doi: 10.1101/2025.05.22.654748. bioRxiv. 2025. PMID: 40475431 Free PMC article. Preprint.
Overcoming resistance to immunotherapy by targeting CD38 in human tumor explants.
Revach OY, Cicerchia AM, Shorer O, Palin CA, Petrova B, Anderson S, Liu B, Park J, Chen L, Mehta A, Wright SJ, McNamee N, Tal-Mason A, Cattaneo G, Tiwari P, Xie H, Sweere JM, Cheng LC, Sigal N, Enrico E, Miljkovic M, Evans SA, Nguyen N, Whidden ME, Srinivasan R, Spitzer MH, Sun Y, Sharova T, Lawless AR, Michaud WA, Rasmussen MQ, Fang J, Brook JR, Chen F, Wang X, Ferrone CR, Lawrence DP, Sullivan RJ, Liu D, Sachdeva UM, Sen DR, Flaherty KT, Manguso RT, Bod L, Kellis M, Boland GM, Yizhak K, Yang J, Kanarek N, Sade-Feldman M, Hacohen N, Jenkins RW. Revach OY, et al. Among authors: brook jr. Cell Rep Med. 2025 Jul 15;6(7):102210. doi: 10.1016/j.xcrm.2025.102210. Epub 2025 Jun 27. Cell Rep Med. 2025. PMID: 40578364 Free PMC article.
Phthalates, bisphenols, and childhood allergic Phenotypes: Findings from two birth cohort studies.
Boissiere-O'Neill T, Lazarevic N, Ponsonby AL, Sly PD, Chen A, Blake TL, Brook JR, Du Berry C, King L, Mandhane PJ, Moraes TJ, Simons E, Subbarao P; CHILD investigator group; BIS investigator group; Vilcins D. Boissiere-O'Neill T, et al. Among authors: brook jr. Environ Pollut. 2026 Jan 15;389:127401. doi: 10.1016/j.envpol.2025.127401. Epub 2025 Nov 19. Environ Pollut. 2026. PMID: 41271151 Free article.
Organophosphate ester flame retardants and plasticizers in house dust and Child Behavior Checklist outcomes: A nested study in the Canadian CHILD Birth Cohort.
Foster SA, Kile ML, Hystad P, Diamond ML, Mandhane PJ, Moraes TJ, Pei J, Scott JA, Simons E, Subbarao P, Takaro TK, Tamana SK, Turvey SE, Brook JR. Foster SA, et al. Among authors: brook jr. J Expo Sci Environ Epidemiol. 2025 Nov 8:10.1038/s41370-025-00821-y. doi: 10.1038/s41370-025-00821-y. Online ahead of print. J Expo Sci Environ Epidemiol. 2025. PMID: 41203828 Free PMC article.
222 results