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Functional integration of the transport of ammonium, glutamate and glutamine in astrocytes.
Brookes N. Brookes N. Neurochem Int. 2000 Aug-Sep;37(2-3):121-9. doi: 10.1016/s0197-0186(00)00015-2. Neurochem Int. 2000. PMID: 10812197 Review.
Further, recent evidence identifies a major transporter of glutamine in astrocytes (System N) as a glutamine/proton exchanger. Potassium can reverse the transmembrane gradient of protons in astrocytes, and increase intracellular glutamine concentration, creating the condit …
Further, recent evidence identifies a major transporter of glutamine in astrocytes (System N) as a glutamine/proton exchanger. Potass …
Characterization of L-alpha-aminoadipic acid transport in cultured rat astrocytes.
Tsai MJ, Chang YF, Schwarcz R, Brookes N. Tsai MJ, et al. Among authors: brookes n. Brain Res. 1996 Nov 25;741(1-2):166-73. doi: 10.1016/s0006-8993(96)00910-9. Brain Res. 1996. PMID: 9001719
Determinants of deoxyglucose uptake in cultured astrocytes: the role of the sodium pump.
Brookes N, Yarowsky PJ. Brookes N, et al. J Neurochem. 1985 Feb;44(2):473-9. doi: 10.1111/j.1471-4159.1985.tb05438.x. J Neurochem. 1985. PMID: 2578179
High-affinity uptake of L-kynurenine by a Na+-independent transporter of neutral amino acids in astrocytes.
Speciale C, Hares K, Schwarcz R, Brookes N. Speciale C, et al. Among authors: brookes n. J Neurosci. 1989 Jun;9(6):2066-72. doi: 10.1523/JNEUROSCI.09-06-02066.1989. J Neurosci. 1989. PMID: 2723766 Free PMC article.
Intracellular acidification induced by passive and active transport of ammonium ions in astrocytes.
Nagaraja TN, Brookes N. Nagaraja TN, et al. Among authors: brookes n. Am J Physiol. 1998 Apr;274(4):C883-91. doi: 10.1152/ajpcell.1998.274.4.C883. Am J Physiol. 1998. PMID: 9575784
Intracellular pH as a regulatory signal in astrocyte metabolism.
Brookes N. Brookes N. Glia. 1997 Sep;21(1):64-73. Glia. 1997. PMID: 9298848 Review.
Mercuric chloride uncouples glutamate uptake from the countertransport of hydroxyl equivalents.
Nagaraja TN, Brookes N. Nagaraja TN, et al. Among authors: brookes n. Am J Physiol. 1996 Nov;271(5 Pt 1):C1487-93. doi: 10.1152/ajpcell.1996.271.5.C1487. Am J Physiol. 1996. PMID: 8944631
In contrast, two other sulfhydryl reagents, p-chloromercuribenzensulfonate and N-ethylmaleimide, failed to discriminate between glutamate-induced acidification and glutamate uptake. ...
In contrast, two other sulfhydryl reagents, p-chloromercuribenzensulfonate and N-ethylmaleimide, failed to discriminate between gluta …
Glutamine transport in mouse cerebral astrocytes.
Nagaraja TN, Brookes N. Nagaraja TN, et al. Among authors: brookes n. J Neurochem. 1996 Apr;66(4):1665-74. doi: 10.1046/j.1471-4159.1996.66041665.x. J Neurochem. 1996. PMID: 8627324
Nevertheless, other evidence supported participation by at least three Na+ -dependent neutral amino acid transporters (systems A, ASC, and N). ...At 700 microM glutamine, the primary uptake route was system N transport, identified on the basis of selective inhibitio …
Nevertheless, other evidence supported participation by at least three Na+ -dependent neutral amino acid transporters (systems A, ASC, and …
Potassium-induced stimulation of glutamate uptake in mouse cerebral astrocytes: the role of intracellular pH.
Judd MG, Nagaraja TN, Brookes N. Judd MG, et al. Among authors: brookes n. J Neurochem. 1996 Jan;66(1):169-76. doi: 10.1046/j.1471-4159.1996.66010169.x. J Neurochem. 1996. PMID: 8522950
Extracellular potassium regulates the glutamine content of astrocytes: mediation by intracellular pH.
Brookes N, Turner RJ. Brookes N, et al. Neurosci Lett. 1993 Sep 17;160(1):73-6. doi: 10.1016/0304-3940(93)9002-7. Neurosci Lett. 1993. PMID: 8247337
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