Brooks AG - Search Results

1

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

Krishnamurthy B, Dudek NL, McKenzie MD, Purcell AW, Brooks AG, Gellert S, Colman PG, Harrison LC, Lew AM, Thomas HE, Kay TW. Krishnamurthy B, et al. Among authors: brooks ag. J Clin Invest. 2006 Dec;116(12):3258-65. doi: 10.1172/JCI29602. J Clin Invest. 2006. PMID: 17143333 Free PMC article.

2

Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex.

Macdonald W, Williams DS, Clements CS, Gorman JJ, Kjer-Nielsen L, Brooks AG, McCluskey J, Rossjohn J, Purcell AW. Macdonald W, et al. Among authors: brooks ag. FEBS Lett. 2002 Sep 11;527(1-3):27-32. doi: 10.1016/s0014-5793(02)03149-6. FEBS Lett. 2002. PMID: 12220628 Free article.

3

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization.

Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, Fontes MR, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: brooks ag. J Immunol. 2002 Nov 1;169(9):5153-60. doi: 10.4049/jimmunol.169.9.5153. J Immunol. 2002. PMID: 12391232

4

The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance.

Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: brooks ag. Structure. 2002 Nov;10(11):1521-32. doi: 10.1016/s0969-2126(02)00878-x. Structure. 2002. PMID: 12429093 Free article.

5

The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state.

Clements CS, Kjer-Nielsen L, MacDonald WA, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Clements CS, et al. Among authors: brooks ag. Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):2131-4. doi: 10.1107/s0907444902015482. Epub 2002 Nov 23. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12454477

6

A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity.

Kjer-Nielsen L, Clements CS, Purcell AW, Brooks AG, Whisstock JC, Burrows SR, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: brooks ag. Immunity. 2003 Jan;18(1):53-64. doi: 10.1016/s1074-7613(02)00513-7. Immunity. 2003. PMID: 12530975 Free article.

7

A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition.

Macdonald WA, Purcell AW, Mifsud NA, Ely LK, Williams DS, Chang L, Gorman JJ, Clements CS, Kjer-Nielsen L, Koelle DM, Burrows SR, Tait BD, Holdsworth R, Brooks AG, Lovrecz GO, Lu L, Rossjohn J, McCluskey J. Macdonald WA, et al. Among authors: brooks ag. J Exp Med. 2003 Sep 1;198(5):679-91. doi: 10.1084/jem.20030066. Epub 2003 Aug 25. J Exp Med. 2003. PMID: 12939341 Free PMC article.

8

Novel strategy for identification of candidate cytotoxic T-cell epitopes from human preproinsulin.

Chang L, Kjer-Nielsen L, Flynn S, Brooks AG, Mannering SI, Honeyman MC, Harrison LC, McCluskey J, Purcell AW. Chang L, et al. Among authors: brooks ag. Tissue Antigens. 2003 Nov;62(5):408-17. doi: 10.1034/j.1399-0039.2003.00122.x. Tissue Antigens. 2003. PMID: 14617048

9

Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.

Kjer-Nielsen L, Dunstone MA, Kostenko L, Ely LK, Beddoe T, Mifsud NA, Purcell AW, Brooks AG, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: brooks ag. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7675-80. doi: 10.1073/pnas.0402295101. Epub 2004 May 10. Proc Natl Acad Sci U S A. 2004. PMID: 15136729 Free PMC article.

10

Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion.

Zernich D, Purcell AW, Macdonald WA, Kjer-Nielsen L, Ely LK, Laham N, Crockford T, Mifsud NA, Bharadwaj M, Chang L, Tait BD, Holdsworth R, Brooks AG, Bottomley SP, Beddoe T, Peh CA, Rossjohn J, McCluskey J. Zernich D, et al. Among authors: brooks ag. J Exp Med. 2004 Jul 5;200(1):13-24. doi: 10.1084/jem.20031680. Epub 2004 Jun 28. J Exp Med. 2004. PMID: 15226359 Free PMC article.

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