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183 results
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Activation of the cannabinoid receptor by delta 9-tetrahydrocannabinol reduces gamma-aminobutyric acid uptake in the globus pallidus.
Maneuf YP, Nash JE, Crossman AR, Brotchie JM. Maneuf YP, et al. Among authors: brotchie jm. Eur J Pharmacol. 1996 Jul 18;308(2):161-4. doi: 10.1016/0014-2999(96)00326-3. Eur J Pharmacol. 1996. PMID: 8840127
alpha2-Adrenoceptor-mediated modulation of the release of GABA and noradrenaline in the rat substantia nigra pars reticulata.
Alachkar A, Brotchie J, Jones OT. Alachkar A, et al. Neurosci Lett. 2006 Mar 6;395(2):138-42. doi: 10.1016/j.neulet.2005.10.069. Epub 2005 Dec 13. Neurosci Lett. 2006. PMID: 16356632
Effects of adenosine A1, dopamine D1 and metabotropic glutamate 5 receptors-modulating agents on locomotion of the reserpinised rats.
Ismayilova N, Crossman A, Verkhratsky A, Brotchie J. Ismayilova N, et al. Eur J Pharmacol. 2004 Aug 23;497(2):187-95. doi: 10.1016/j.ejphar.2004.06.030. Eur J Pharmacol. 2004. PMID: 15306204
Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot study.
Sieradzan KA, Fox SH, Hill M, Dick JP, Crossman AR, Brotchie JM. Sieradzan KA, et al. Among authors: brotchie jm. Neurology. 2001 Dec 11;57(11):2108-11. doi: 10.1212/wnl.57.11.2108. Neurology. 2001. PMID: 11739835 Clinical Trial.
Delta-opioid receptor agonists as a therapeutic approach in Parkinson's disease.
Hill MP, Hille CJ, Brotchie JM. Hill MP, et al. Among authors: brotchie jm. Drug News Perspect. 2000 Jun;13(5):261-8. Drug News Perspect. 2000. PMID: 12937640
5-hydroxytryptamine (5-HT, serotonin) and Parkinson's disease - opportunities for novel therapeutics to reduce the problems of levodopa therapy.
Nicholson SL, Brotchie JM. Nicholson SL, et al. Among authors: brotchie jm. Eur J Neurol. 2002 Nov;9 Suppl 3:1-6. doi: 10.1046/j.1468-1331.9.s3.1.x. Eur J Neurol. 2002. PMID: 12464115 Review.
On the role of enkephalin cotransmission in the GABAergic striatal efferents to the globus pallidus.
Maneuf YP, Mitchell IJ, Crossman AR, Brotchie JM. Maneuf YP, et al. Among authors: brotchie jm. Exp Neurol. 1994 Jan;125(1):65-71. doi: 10.1006/exnr.1994.1007. Exp Neurol. 1994. PMID: 8307125
Functional implications of kappa opioid receptor-mediated modulation of glutamate transmission in the output regions of the basal ganglia in rodent and primate models of Parkinson's disease.
Maneuf YP, Mitchell IJ, Crossman AR, Woodruff GN, Brotchie JM. Maneuf YP, et al. Among authors: brotchie jm. Brain Res. 1995 Jun 12;683(1):102-8. doi: 10.1016/0006-8993(95)00358-w. Brain Res. 1995. PMID: 7552334
Alleviation of parkinsonism by antagonism of excitatory amino acid transmission in the medial segment of the globus pallidus in rat and primate.
Brotchie JM, Mitchell IJ, Sambrook MA, Crossman AR. Brotchie JM, et al. Mov Disord. 1991;6(2):133-8. doi: 10.1002/mds.870060208. Mov Disord. 1991. PMID: 1647492
D-[3H]aspartate and [14C]GABA uptake in the basal ganglia of rats following lesions in the subthalamic region suggest a role for excitatory amino acid but not GABA-mediated transmission in subthalamic nucleus efferents.
Brotchie JM, Crossman AR. Brotchie JM, et al. Exp Neurol. 1991 Aug;113(2):171-81. doi: 10.1016/0014-4886(91)90173-a. Exp Neurol. 1991. PMID: 1651255 No abstract available.
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