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Structure of the cyclin-dependent kinase inhibitor p19Ink4d.
Luh FY, Archer SJ, Domaille PJ, Smith BO, Owen D, Brotherton DH, Raine AR, Xu X, Brizuela L, Brenner SL, Laue ED. Luh FY, et al. Among authors: brotherton dh. Nature. 1997 Oct 30;389(6654):999-1003. doi: 10.1038/40202. Nature. 1997. PMID: 9353127
A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity.
Montagnoli A, Valsasina B, Croci V, Menichincheri M, Rainoldi S, Marchesi V, Tibolla M, Tenca P, Brotherton D, Albanese C, Patton V, Alzani R, Ciavolella A, Sola F, Molinari A, Volpi D, Avanzi N, Fiorentini F, Cattoni M, Healy S, Ballinari D, Pesenti E, Isacchi A, Moll J, Bensimon A, Vanotti E, Santocanale C. Montagnoli A, et al. Nat Chem Biol. 2008 Jun;4(6):357-65. doi: 10.1038/nchembio.90. Epub 2008 May 11. Nat Chem Biol. 2008. PMID: 18469809
Drf1, a novel regulatory subunit for human Cdc7 kinase.
Montagnoli A, Bosotti R, Villa F, Rialland M, Brotherton D, Mercurio C, Berthelsen J, Santocanale C. Montagnoli A, et al. EMBO J. 2002 Jun 17;21(12):3171-81. doi: 10.1093/emboj/cdf290. EMBO J. 2002. PMID: 12065429 Free PMC article.
Mechanism of substrate binding and transport in BASS transporters.
Becker P, Naughton FB, Brotherton DH, Pacheco-Gomez R, Beckstein O, Cameron AD. Becker P, et al. Among authors: brotherton dh. bioRxiv [Preprint]. 2023 Aug 16:2023.06.02.543391. doi: 10.1101/2023.06.02.543391. bioRxiv. 2023. PMID: 37645971 Free PMC article. Updated. Preprint.
16 results