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Page 1
Activating GCN2 and subsequently the Unfolded Protein Response with the small oral molecule NXP800 delays tumor growth in osteosarcoma.
Racineau E, Lallier M, Postec A, Amiaud J, Thépault RA, Brion R, Battaglia S, Charrier C, Colle MA, Brounais-Le Royer B, Baud'huin M, Verrecchia F, Ory B, Georges S, Lamoureux F. Racineau E, et al. Among authors: brounais le royer b. Cell Death Discov. 2026 Feb 5;12(1):94. doi: 10.1038/s41420-026-02941-2. Cell Death Discov. 2026. PMID: 41644942 Free PMC article.
Transcriptional regulation of KCNA2 coding Kv1.2 by EWS::FLI1: involvement in controlling the YAP/Hippo signalling pathway and cell proliferation.
Dupuy M, Postec A, Mullard M, Chantôme A, Hulin P, Brion R, Gueguinou M, Regnier L, Potier-Cartereau M, Brounais-Le Royer B, Baud'huin M, Georges S, Lamoureux F, Ory B, Rédini F, Vandier C, Verrecchia F. Dupuy M, et al. Among authors: brounais le royer b. Cell Commun Signal. 2024 Dec 18;22(1):602. doi: 10.1186/s12964-024-01981-4. Cell Commun Signal. 2024. PMID: 39695664 Free PMC article.
Chimeric protein EWS::FLI1 drives cell proliferation in Ewing Sarcoma via aberrant expression of KCNN1/SK1 and dysregulation of calcium signaling.
Dupuy M, Gueguinou M, Postec A, Brion R, Tesfaye R, Mullard M, Regnier L, Amiaud J, Hubsch C, Potier-Cartereau M, Chantôme A, Brounais-Le Royer B, Baud'huin M, Georges S, Lamoureux F, Ory B, Entz-Werlé N, Delattre O, Rédini F, Vandier C, Verrecchia F. Dupuy M, et al. Among authors: brounais le royer b. Oncogene. 2025 Jan;44(2):79-91. doi: 10.1038/s41388-024-03199-7. Epub 2024 Nov 1. Oncogene. 2025. PMID: 39487324 Free PMC article.
Ewing sarcoma from molecular biology to the clinic.
Dupuy M, Lamoureux F, Mullard M, Postec A, Regnier L, Baud'huin M, Georges S, Brounais-Le Royer B, Ory B, Rédini F, Verrecchia F. Dupuy M, et al. Among authors: brounais le royer b. Front Cell Dev Biol. 2023 Sep 11;11:1248753. doi: 10.3389/fcell.2023.1248753. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37752913 Free PMC article. Review.
Tracking Targets of Dynamic Super-Enhancers in Vitro to Better Characterize Osteoclastogenesis and to Evaluate the Effect of Diuron on the Maturation of Human Bone Cells.
Tesfaye RA, Lavaud M, Charrier C, Brounais-Le Royer B, Cartron PF, Verrecchia F, Baud'huin M, Lamoureux F, Georges S, Ory B. Tesfaye RA, et al. Among authors: brounais le royer b. Environ Health Perspect. 2023 Jun;131(6):67007. doi: 10.1289/EHP11690. Epub 2023 Jun 12. Environ Health Perspect. 2023. PMID: 37307168 Free PMC article.
Overexpression of the Ubiquitin Specific Proteases USP43, USP41, USP27x and USP6 in Osteosarcoma Cell Lines: Inhibition of Osteosarcoma Tumor Growth and Lung Metastasis Development by the USP Antagonist PR619.
Lavaud M, Mullard M, Tesfaye R, Amiaud J, Legrand M, Danieau G, Brion R, Morice S, Regnier L, Dupuy M, Brounais-Le Royer B, Lamoureux F, Ory B, Rédini F, Verrecchia F. Lavaud M, et al. Among authors: brounais le royer b. Cells. 2021 Aug 31;10(9):2268. doi: 10.3390/cells10092268. Cells. 2021. PMID: 34571917 Free PMC article.
19 results