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Identification of the likely translational start of Mycobacterium tuberculosis GyrB.
Karkare S, Brown AC, Parish T, Maxwell A. Karkare S, et al. BMC Res Notes. 2013 Jul 15;6:274. doi: 10.1186/1756-0500-6-274. BMC Res Notes. 2013. PMID: 23856181 Free PMC article.
Rapid Whole-Genome Sequencing of Mycobacterium tuberculosis Isolates Directly from Clinical Samples.
Brown AC, Bryant JM, Einer-Jensen K, Holdstock J, Houniet DT, Chan JZ, Depledge DP, Nikolayevskyy V, Broda A, Stone MJ, Christiansen MT, Williams R, McAndrew MB, Tutill H, Brown J, Melzer M, Rosmarin C, McHugh TD, Shorten RJ, Drobniewski F, Speight G, Breuer J. Brown AC, et al. J Clin Microbiol. 2015 Jul;53(7):2230-7. doi: 10.1128/JCM.00486-15. Epub 2015 May 13. J Clin Microbiol. 2015. PMID: 25972414 Free PMC article.
Mycobacterium tuberculosis H37Rv has a single nucleotide polymorphism in PhoR which affects cell wall hydrophobicity and gene expression.
Schreuder LJ, Carroll P, Muwanguzi-Karugaba J, Kokoczka R, Brown AC, Parish T. Schreuder LJ, et al. Microbiology. 2015 Apr;161(Pt 4):765-773. doi: 10.1099/mic.0.000036. Epub 2015 Jan 29. Microbiology. 2015. PMID: 25635271
Micrococcin P1 - A bactericidal thiopeptide active against Mycobacterium tuberculosis.
Degiacomi G, Personne Y, Mondésert G, Ge X, Mandava CS, Hartkoorn RC, Boldrin F, Goel P, Peisker K, Benjak A, Barrio MB, Ventura M, Brown AC, Leblanc V, Bauer A, Sanyal S, Cole ST, Lagrange S, Parish T, Manganelli R. Degiacomi G, et al. Tuberculosis (Edinb). 2016 Sep;100:95-101. doi: 10.1016/ Epub 2016 Jul 27. Tuberculosis (Edinb). 2016. PMID: 27553416
Deletion of SenX3-RegX3, a key two-component regulatory system of Mycobacterium smegmatis, results in growth defects under phosphate-limiting conditions.
James JN, Hasan ZU, Ioerger TR, Brown AC, Personne Y, Carroll P, Ikeh M, Tilston-Lunel NL, Palavecino C, Sacchettini JC, Parish T. James JN, et al. Microbiology. 2012 Nov;158(Pt 11):2724-2731. doi: 10.1099/mic.0.060319-0. Epub 2012 Sep 6. Microbiology. 2012. PMID: 22956756
The dUTPase enzyme is essential in Mycobacterium smegmatis.
Pecsi I, Hirmondo R, Brown AC, Lopata A, Parish T, Vertessy BG, Tóth J. Pecsi I, et al. PLoS One. 2012;7(5):e37461. doi: 10.1371/journal.pone.0037461. Epub 2012 May 24. PLoS One. 2012. PMID: 22655049 Free PMC article.
The nonmevalonate pathway of isoprenoid biosynthesis in Mycobacterium tuberculosis is essential and transcriptionally regulated by Dxs.
Brown AC, Eberl M, Crick DC, Jomaa H, Parish T. Brown AC, et al. J Bacteriol. 2010 May;192(9):2424-33. doi: 10.1128/JB.01402-09. Epub 2010 Feb 19. J Bacteriol. 2010. PMID: 20172995 Free PMC article.
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