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Role for NLRP3 Inflammasome-mediated, IL-1β-Dependent Responses in Severe, Steroid-Resistant Asthma.
Kim RY, Pinkerton JW, Essilfie AT, Robertson AAB, Baines KJ, Brown AC, Mayall JR, Ali MK, Starkey MR, Hansbro NG, Hirota JA, Wood LG, Simpson JL, Knight DA, Wark PA, Gibson PG, O'Neill LAJ, Cooper MA, Horvat JC, Hansbro PM. Kim RY, et al. Among authors: brown ac. Am J Respir Crit Care Med. 2017 Aug 1;196(3):283-297. doi: 10.1164/rccm.201609-1830OC. Am J Respir Crit Care Med. 2017. PMID: 28252317
Murine models of infectious exacerbations of airway inflammation.
Starkey MR, Jarnicki AG, Essilfie AT, Gellatly SL, Kim RY, Brown AC, Foster PS, Horvat JC, Hansbro PM. Starkey MR, et al. Among authors: brown ac. Curr Opin Pharmacol. 2013 Jun;13(3):337-44. doi: 10.1016/j.coph.2013.03.005. Epub 2013 Apr 6. Curr Opin Pharmacol. 2013. PMID: 23566696 Review.
Mucosal production of uric acid by airway epithelial cells contributes to particulate matter-induced allergic sensitization.
Gold MJ, Hiebert PR, Park HY, Stefanowicz D, Le A, Starkey MR, Deane A, Brown AC, Liu G, Horvat JC, Ibrahim ZA, Sukkar MB, Hansbro PM, Carlsten C, VanEeden S, Sin DD, McNagny KM, Knight DA, Hirota JA. Gold MJ, et al. Among authors: brown ac. Mucosal Immunol. 2016 May;9(3):809-20. doi: 10.1038/mi.2015.104. Epub 2015 Oct 28. Mucosal Immunol. 2016. PMID: 26509876 Free article.
Polycomb repressive complex 2 is a critical mediator of allergic inflammation.
Keenan CR, Iannarella N, Garnham AL, Brown AC, Kim RY, Horvat JC, Hansbro PM, Nutt SL, Allan RS. Keenan CR, et al. Among authors: brown ac. JCI Insight. 2019 May 16;4(10):e127745. doi: 10.1172/jci.insight.127745. eCollection 2019 May 16. JCI Insight. 2019. PMID: 31092733 Free PMC article.
Critical role for iron accumulation in the pathogenesis of fibrotic lung disease.
Ali MK, Kim RY, Brown AC, Donovan C, Vanka KS, Mayall JR, Liu G, Pillar AL, Jones-Freeman B, Xenaki D, Borghuis T, Karim R, Pinkerton JW, Aryal R, Heidari M, Martin KL, Burgess JK, Oliver BG, Trinder D, Johnstone DM, Milward EA, Hansbro PM, Horvat JC. Ali MK, et al. Among authors: brown ac. J Pathol. 2020 May;251(1):49-62. doi: 10.1002/path.5401. Epub 2020 Mar 30. J Pathol. 2020. PMID: 32083318
532 results