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Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.
Hewitt NJ, Lechón MJ, Houston JB, Hallifax D, Brown HS, Maurel P, Kenna JG, Gustavsson L, Lohmann C, Skonberg C, Guillouzo A, Tuschl G, Li AP, LeCluyse E, Groothuis GM, Hengstler JG. Hewitt NJ, et al. Among authors: brown hs. Drug Metab Rev. 2007;39(1):159-234. doi: 10.1080/03602530601093489. Drug Metab Rev. 2007. PMID: 17364884 Review.
Response to Patterson et al.
Wilson KJ, Brown HS 3rd. Wilson KJ, et al. Among authors: brown hs 3rd. Prev Med. 2020 Feb 6:106015. doi: 10.1016/j.ypmed.2020.106015. Online ahead of print. Prev Med. 2020. PMID: 32035871 No abstract available.
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