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729 results
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C-terminal phosphorylation of NaV1.5 impairs FGF13-dependent regulation of channel inactivation.
Burel S, Coyan FC, Lorenzini M, Meyer MR, Lichti CF, Brown JH, Loussouarn G, Charpentier F, Nerbonne JM, Townsend RR, Maier LS, Marionneau C. Burel S, et al. J Biol Chem. 2017 Oct 20;292(42):17431-17448. doi: 10.1074/jbc.M117.787788. Epub 2017 Sep 7. J Biol Chem. 2017. PMID: 28882890 Free PMC article.
Yes-associated protein (YAP) mediates adaptive cardiac hypertrophy in response to pressure overload.
Byun J, Del Re DP, Zhai P, Ikeda S, Shirakabe A, Mizushima W, Miyamoto S, Brown JH, Sadoshima J. Byun J, et al. Among authors: brown jh. J Biol Chem. 2019 Mar 8;294(10):3603-3617. doi: 10.1074/jbc.RA118.006123. Epub 2019 Jan 11. J Biol Chem. 2019. PMID: 30635403 Free PMC article.
Selective coupling of the S1P3 receptor subtype to S1P-mediated RhoA activation and cardioprotection.
Yung BS, Brand CS, Xiang SY, Gray CB, Means CK, Rosen H, Chun J, Purcell NH, Brown JH, Miyamoto S. Yung BS, et al. J Mol Cell Cardiol. 2017 Feb;103:1-10. doi: 10.1016/j.yjmcc.2016.12.008. Epub 2016 Dec 23. J Mol Cell Cardiol. 2017. PMID: 28017639 Free PMC article.
Drp1 and Mitochondrial Autophagy Lend a Helping Hand in Adaptation to Pressure Overload.
Miyamoto S, Brown JH. Miyamoto S, et al. Circulation. 2016 Mar 29;133(13):1225-7. doi: 10.1161/CIRCULATIONAHA.116.021796. Epub 2016 Feb 25. Circulation. 2016. PMID: 26915632 Free PMC article. No abstract available.
The promise of CaMKII inhibition for heart disease: preventing heart failure and arrhythmias.
Westenbrink BD, Edwards AG, McCulloch AD, Brown JH. Westenbrink BD, et al. Expert Opin Ther Targets. 2013 Aug;17(8):889-903. doi: 10.1517/14728222.2013.809064. Epub 2013 Jun 24. Expert Opin Ther Targets. 2013. PMID: 23789646 Free PMC article. Review.
APJ acts as a dual receptor in cardiac hypertrophy.
Scimia MC, Hurtado C, Ray S, Metzler S, Wei K, Wang J, Woods CE, Purcell NH, Catalucci D, Akasaka T, Bueno OF, Vlasuk GP, Kaliman P, Bodmer R, Smith LH, Ashley E, Mercola M, Brown JH, Ruiz-Lozano P. Scimia MC, et al. Nature. 2012 Aug 16;488(7411):394-8. doi: 10.1038/nature11263. Nature. 2012. PMID: 22810587 Free PMC article.
CaMKIIδC slows [Ca]i decline in cardiac myocytes by promoting Ca sparks.
Guo T, Zhang T, Ginsburg KS, Mishra S, Brown JH, Bers DM. Guo T, et al. Biophys J. 2012 Jun 6;102(11):2461-70. doi: 10.1016/j.bpj.2012.04.015. Epub 2012 Jun 5. Biophys J. 2012. PMID: 22713561 Free PMC article.
Crossing signals: relationships between β-adrenergic stimulation and CaMKII activation.
Grimm M, Ling H, Brown JH. Grimm M, et al. Heart Rhythm. 2011 Aug;8(8):1296-8. doi: 10.1016/j.hrthm.2011.02.027. Epub 2011 Feb 23. Heart Rhythm. 2011. PMID: 21354330 Free PMC article. No abstract available.
RhoA protects the mouse heart against ischemia/reperfusion injury.
Xiang SY, Vanhoutte D, Del Re DP, Purcell NH, Ling H, Banerjee I, Bossuyt J, Lang RA, Zheng Y, Matkovich SJ, Miyamoto S, Molkentin JD, Dorn GW 2nd, Brown JH. Xiang SY, et al. J Clin Invest. 2011 Aug;121(8):3269-76. doi: 10.1172/JCI44371. Epub 2011 Jul 11. J Clin Invest. 2011. PMID: 21747165 Free PMC article.
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